Version 5.4
Mus musculus Gene: Helz
Summary
InnateDB Gene IDBG-213704.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Helz
Gene Name helicase with zinc finger domain
Synonyms 3110078M01Rik; 9430093I07Rik; 9630002H22Rik; AI851979; DRHC
Species Mus musculus
Ensembl Gene ENSMUSG00000020721
Encoded Proteins
IDBP-213706
helicase with zinc finger domain
IDBP-213708
helicase with zinc finger domain
IDBP-268127
helicase with zinc finger domain
IDBP-532511
helicase with zinc finger domain
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198265:
HELZ is a member of the superfamily I class of RNA helicases. RNA helicases alter the conformation of RNA by unwinding double-stranded regions, thereby altering the biologic activity of the RNA molecule and regulating access to other proteins (Wagner et al., 1999 [PubMed 10471385]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:107547930-107693826
Strand Forward strand
Band E1
Transcripts
ENSMUST00000100305 ENSMUSP00000097878
ENSMUST00000075012 ENSMUSP00000074533
ENSMUST00000106746 ENSMUSP00000102357
ENSMUST00000141730
ENSMUST00000133862 ENSMUSP00000117498
ENSMUST00000143634
ENSMUST00000154847
ENSMUST00000153080
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0044822 poly(A) RNA binding
GO:0046872 metal ion binding
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005634 nucleus
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000198265
View Gene Order
ENSBTAG00000004746
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.272047 Mm.34220 Mm.383745 Mm.392689 Mm.394603 Mm.408586 Mm.408605 Mm.408820 Mm.490425
RefSeq NM_198298 XM_006534504 XM_006534505 XM_006534506 XM_006534507
OMIM
CCDS CCDS25569
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca