Version 5.4
Mus musculus Gene: Myt1
Summary
InnateDB Gene IDBG-214243.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Myt1
Gene Name myelin transcription factor 1
Synonyms Nzf2; Nzf2a; Nzf2b; Nztf2
Species Mus musculus
Ensembl Gene ENSMUSG00000010505
Encoded Proteins
IDBP-214245
myelin transcription factor 1
IDBP-263844
myelin transcription factor 1
IDBP-263846
myelin transcription factor 1
IDBP-540858
myelin transcription factor 1
IDBP-539436
myelin transcription factor 1
IDBP-542769
myelin transcription factor 1
IDBP-790205
myelin transcription factor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the myelin transcription factor 1 gene family. The encoded protein, a zinc finger DNA-binding protein, is involved in regulation of oligodendrocyte differentiation and proliferation in the developing central nervous system. The gene product has a role in remyelination through regeneration of oligodendrocyte lineage cells in response to demyelination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:181763332-181827797
Strand Forward strand
Band H4
Transcripts
ENSMUST00000081125 ENSMUSP00000079900
ENSMUST00000108757 ENSMUSP00000104388
ENSMUST00000108756 ENSMUSP00000104387
ENSMUST00000156190
ENSMUST00000129856 ENSMUSP00000122011
ENSMUST00000130079
ENSMUST00000129843 ENSMUSP00000115697
ENSMUST00000142245
ENSMUST00000135744 ENSMUSP00000121394
ENSMUST00000148766
ENSMUST00000183403 ENSMUSP00000139356
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001158 enhancer sequence-specific DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007399 nervous system development
GO:0030154 cell differentiation
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000196132
View Gene Order
ENSBTAG00000006352
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8CFC2
TrEMBL
UniProt Splice Variant
Entrez Gene 17932
UniGene Mm.400017 Mm.458718
RefSeq NM_001171616 XM_006500579 NM_001171615 NM_001171680 NM_008665 XM_006500577 XM_006500578 XM_006500580
OMIM
CCDS CCDS50857 CCDS17223 CCDS50856
HPRD
IMGT
MGI ID MGI:1100535
MGI Symbol Myt1
EMBL AB082378 AB093267 AF004294 AL845173 BC063252
GenPept AAC53456 AAH63252 BAC16512 BAC41451 CAM20798 CAM20799
RNA Seq Atlas 17932

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca