Version 5.4
Homo sapiens Gene: RERG
Summary
InnateDB Gene IDBG-21429.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RERG
Gene Name RAS-like, estrogen-regulated, growth inhibitor
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000134533
Encoded Proteins
IDBP-21431
RAS-like, estrogen-regulated, growth inhibitor
IDBP-597573
RAS-like, estrogen-regulated, growth inhibitor
IDBP-585855
RAS-like, estrogen-regulated, growth inhibitor
IDBP-585554
RAS-like, estrogen-regulated, growth inhibitor
IDBP-596596
RAS-like, estrogen-regulated, growth inhibitor
IDBP-602968
RAS-like, estrogen-regulated, growth inhibitor
IDBP-586583
RAS-like, estrogen-regulated, growth inhibitor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary RERG, a member of the RAS superfamily of GTPases, inhibits cell proliferation and tumor formation (Finlin et al., 2001 [PubMed 11533059]).[supplied by OMIM, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:15107783-15348675
Strand Reverse strand
Band p12.3
Transcripts
ENST00000256953 ENSP00000256953
ENST00000393736 ENSP00000440887
ENST00000437578
ENST00000538313 ENSP00000441505
ENST00000536465 ENSP00000438280
ENST00000546331 ENSP00000444485
ENST00000545567 ENSP00000439532
ENST00000537647 ENSP00000441860
ENST00000537717
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0019003 GDP binding
GO:0030331 estrogen receptor binding
Biological Process
GO:0006184 GTP catabolic process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0008285 negative regulation of cell proliferation
GO:0009725 response to hormone
GO:0015031 protein transport
GO:0030308 negative regulation of cell growth
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005829 cytosol
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030222
View Gene Order
ENSBTAG00000002174
Not yet available
Cross-References
SwissProt
TrEMBL F5GYR1
UniProt Splice Variant
Entrez Gene 85004
UniGene Hs.199487
RefSeq NM_001190726 NM_032918
HUGO HGNC:15980
OMIM 612664
CCDS CCDS53753 CCDS8673
HPRD 15238
IMGT
EMBL AC007543 AC022334 AC092183
GenPept
RNA Seq Atlas 85004

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca