Version 5.4
Mus musculus Gene: Recql5
Summary
InnateDB Gene IDBG-214370.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Recql5
Gene Name RecQ protein-like 5
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000020752
Encoded Proteins
IDBP-214372
RecQ protein-like 5
IDBP-716604
IDBP-716320
IDBP-718244
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000108469:
The protein encoded by this gene is a helicase that is important for genome stability. The encoded protein also prevents aberrant homologous recombination by displacing RAD51 from ssDNA. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:115892595-115933477
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000021097 ENSMUSP00000021097
ENSMUST00000140174 ENSMUSP00000136506
ENSMUST00000136774
ENSMUST00000131578 ENSMUSP00000136178
ENSMUST00000144824
ENSMUST00000147172
ENSMUST00000134208 ENSMUSP00000137157
ENSMUST00000156776
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 35 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 35 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000993 RNA polymerase II core binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006200 ATP catabolic process
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0007067 mitotic nuclear division
GO:0008152 metabolic process
GO:0032508 DNA duplex unwinding
GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter
GO:0051304 chromosome separation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0016591 DNA-directed RNA polymerase II, holoenzyme
GO:0031965 nuclear membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000108469
View Gene Order
ENSBTAG00000011715
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.379351 Mm.421553
RefSeq NM_130454 XM_006532357 XM_006532358 XM_006532359 XM_006532360 XM_006532361 XM_006532362 XM_006532363 XM_006532364
OMIM
CCDS CCDS25650
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca