Version 5.4
Mus musculus Gene: Cbx4
Summary
InnateDB Gene IDBG-214671.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cbx4
Gene Name chromobox 4
Synonyms MPc2; PC2
Species Mus musculus
Ensembl Gene ENSMUSG00000039989
Encoded Proteins
IDBP-214673
chromobox homolog 4 (Drosophila Pc class)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000141582:
Gene Information
Type Protein coding
Genomic Location Chromosome 11:119077573-119086221
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000026665 ENSMUSP00000026665
ENSMUST00000145058
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 73 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 73 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
GO:0003727 single-stranded RNA binding
GO:0005515 protein binding
GO:0016874 ligase activity
GO:0019899 enzyme binding
GO:0032183 SUMO binding
GO:0035064 methylated histone binding
GO:0044212 transcription regulatory region DNA binding
GO:0051219 phosphoprotein binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0016568 chromatin modification
GO:0016925 protein sumoylation
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005794 Golgi apparatus
GO:0016604 nuclear body
GO:0016607 nuclear speck
GO:0031519 PcG protein complex
GO:0035102 PRC1 complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000141582
View Gene Order
ENSBTAG00000009782
Not yet available
Pathways
NETPATH
REACTOME
REACT_188970
Oxidative Stress Induced Senescence pathway
REACT_188957
Cellular responses to stress pathway
REACT_188820
Cellular Senescence pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_120956
Cellular responses to stress pathway
REACT_169274
Cellular Senescence pathway
REACT_169436
Oxidative Stress Induced Senescence pathway
KEGG
INOH
PID NCI
rb_1pathway
Regulation of retinoblastoma protein
cmyb_pathway
C-MYB transcription factor network
Cross-References
SwissProt O55187
TrEMBL Q8C9Z5
UniProt Splice Variant
Entrez Gene 12418
UniGene Mm.268070 Mm.471550
RefSeq NM_007625
OMIM
CCDS CCDS25710
HPRD
IMGT
MGI ID MGI:1195985
MGI Symbol Cbx4
EMBL AK040138 BC117801 BC117802 U63387
GenPept AAB96874 AAI17802 AAI17803 BAC30519
RNA Seq Atlas 12418

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca