Version 5.4
Homo sapiens Gene: AQP8
Summary
InnateDB Gene IDBG-21578.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AQP8
Gene Name aquaporin 8
Synonyms AQP-8
Species Homo sapiens
Ensembl Gene ENSG00000103375
Encoded Proteins
IDBP-21580
aquaporin 8
IDBP-752123
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Aquaporin 8 (AQP8) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 8 mRNA is found in pancreas and colon but not other tissues. [provided by RefSeq, Jul 2008]
Aquaporin 8 (AQP8) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 8 mRNA is found in pancreas and colon but not other tissues. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:25215731-25228940
Strand Forward strand
Band p12.1
Transcripts
ENST00000219660 ENSP00000219660
ENST00000566125 ENSP00000454457
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0015250 water channel activity
Biological Process
GO:0006810 transport
GO:0006833 water transport
GO:0015722 canalicular bile acid transport
GO:0055085 transmembrane transport
GO:0071320 cellular response to cAMP
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0045177 apical part of cell
GO:0046691 intracellular canaliculus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030762
View Gene Order
ENSBTAG00000020184
Not yet available
Pathways
NETPATH
REACTOME
REACT_23826
Passive transport by Aquaporins pathway
REACT_120956
Cellular responses to stress pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_172715
Detoxification of Reactive Oxygen Species pathway
REACT_23887
Aquaporin-mediated transport pathway
KEGG
hsa04976
Bile secretion pathway
INOH
PID NCI
Cross-References
SwissProt O94778
TrEMBL
UniProt Splice Variant
Entrez Gene 343
UniGene
RefSeq NM_001169
HUGO HGNC:642
OMIM 603750
CCDS CCDS10626
HPRD 04778
IMGT
EMBL AB013456 AF067797 BC040630
GenPept AAF19050 AAH40630 BAA34223
RNA Seq Atlas 343

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca