InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: STRAP

Summary

InnateDB Gene

IDBG-21633.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

STRAP

Gene Name

serine/threonine kinase receptor associated protein

Synonyms

MAWD; PT-WD; UNRIP

Species

Homo sapiens

Ensembl Gene

ENSG00000023734

Encoded Proteins

IDBP-21635

serine/threonine kinase receptor associated protein

IDBP-368431

serine/threonine kinase receptor associated protein

IDBP-599532

serine/threonine kinase receptor associated protein

IDBP-588821

serine/threonine kinase receptor associated protein

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 12:15882391-15903478

Strand

Forward strand

Band

p12.3

Transcripts

ENST00000025399	ENSP00000025399
ENST00000419869	ENSP00000392270
ENST00000541731	ENSP00000445693
ENST00000536737
ENST00000538718	ENSP00000445814
ENST00000539887

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 69 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	69 [view]
Protein-Protein	62 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	4 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding
GO:0005515	protein binding
GO:0016301	kinase activity
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0000387	spliceosomal snRNP assembly
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0010633	negative regulation of epithelial cell migration
GO:0010719	negative regulation of epithelial to mesenchymal transition
GO:0016310	phosphorylation
GO:0030277	maintenance of gastrointestinal epithelium
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
GO:0050680	negative regulation of epithelial cell proliferation
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0030054	cell junction
GO:0032797	SMN complex
GO:0034719	SMN-Sm protein complex