Version 5.4
Homo sapiens Gene: GTF3C1
Summary
InnateDB Gene IDBG-21912.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GTF3C1
Gene Name general transcription factor IIIC, polypeptide 1, alpha 220kDa
Synonyms TFIIIC; TFIIIC220; TFIIICalpha
Species Homo sapiens
Ensembl Gene ENSG00000077235
Encoded Proteins
IDBP-21914
general transcription factor IIIC, polypeptide 1, alpha 220kDa
IDBP-748501
IDBP-746666
IDBP-747047
IDBP-746191
IDBP-749958
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 16:27459555-27549913
Strand Reverse strand
Band p12.1
Transcripts
ENST00000356183 ENSP00000348510
ENST00000568569 ENSP00000456187
ENST00000569653 ENSP00000457449
ENST00000562609
ENST00000569394
ENST00000566779
ENST00000570129
ENST00000564664 ENSP00000457476
ENST00000571886 ENSP00000459231
ENST00000564747
ENST00000561623 ENSP00000455417
ENST00000567843
ENST00000567806
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 66 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 66 [view]
Protein-Protein 66 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006383 transcription from RNA polymerase III promoter
GO:0009303 rRNA transcription
GO:0009304 tRNA transcription
GO:0010467 gene expression
GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter
GO:0042797 tRNA transcription from RNA polymerase III promoter
Cellular Component
GO:0000127 transcription factor TFIIIC complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0016020 membrane
GO:0030529 ribonucleoprotein complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000032777
View Gene Order
ENSBTAG00000006126
Not yet available
Pathways
NETPATH
REACTOME
REACT_22339
RNA Polymerase III Abortive And Retractive Initiation pathway
REACT_1036
RNA Polymerase III Transcription Initiation From Type 2 Promoter pathway
REACT_347
RNA Polymerase III Transcription Initiation From Type 1 Promoter pathway
REACT_281
RNA Polymerase III Transcription Initiation pathway
REACT_1371
RNA Polymerase III Transcription pathway
REACT_21352
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_71
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q7Z7H4
UniProt Splice Variant
Entrez Gene 2975
UniGene Hs.371718 Hs.707935
RefSeq NM_001286242 NM_001520
HUGO HGNC:4664
OMIM 603246
CCDS CCDS32414 CCDS66988
HPRD 07540
IMGT
EMBL BC052642
GenPept AAH52642
RNA Seq Atlas 2975

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca