InnateDB Gene
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IDBG-21935.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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NCF1C
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Gene Name
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neutrophil cytosolic factor 1C pseudogene
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Synonyms
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Species
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Homo sapiens
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Ensembl Gene
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ENSG00000165178
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Encoded Proteins
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Protein Structure
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Useful resources
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Stemformatics
EHFPI
ImmGen
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Summary |
The neutrophil cytosolic factor 1 (NCF1) gene encodes the 47 kDa cytosolic subunit of neutrophil NADPH oxidase, which produces superoxide anion. The NCF1 gene is located in close proximity to two highly similar, multi-exon pseudogenes at chromosome 7q11.23, corresponding to this gene record and GeneID:654816. The two pseudogenes contain a dinucleotide deletion (delta-GT) in exon 2 that results in a frameshift and truncation of the open reading frame, and neither pseudogene is likely to express a protein. Recombination events between the pseudogenes and the functional NCF1 gene can inactivate the NCF1 gene and result in chronic granulomatous disease. [provided by RefSeq, Nov 2009]
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Type |
unprocessed_pseudogene
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Genomic Location
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Chromosome 7:75156639-75172044
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Strand
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Reverse strand
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Band
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q11.23
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Transcripts
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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No orthologs found for this gene |
SwissProt
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TrEMBL
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UniProt Splice Variant
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Entrez Gene
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UniGene
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RefSeq
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HUGO
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OMIM
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CCDS
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HPRD |
01990
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IMGT
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EMBL
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GenPept
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RNA Seq Atlas
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