Version 5.4
Homo sapiens Gene: CSN2
Summary
InnateDB Gene IDBG-22064.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CSN2
Gene Name casein beta
Synonyms CASB
Species Homo sapiens
Ensembl Gene ENSG00000135222
Encoded Proteins
IDBP-22066
casein beta
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 4:69955256-69961007
Strand Reverse strand
Band q13.3
Transcripts
ENST00000353151 ENSP00000341030
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 20 [view]
Protein-Protein 19 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004857 enzyme inhibitor activity
GO:0005215 transporter activity
GO:0005509 calcium ion binding
Biological Process
GO:0006810 transport
GO:0006816 calcium ion transport
GO:0007595 lactation
GO:0043086 negative regulation of catalytic activity
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000063157
View Gene Order
ENSBTAG00000002632
Not yet available
Pathways
NETPATH
REACTOME
REACT_116022
Nuclear signaling by ERBB4 pathway
REACT_115596
Signaling by ERBB4 pathway
REACT_111102
Signal Transduction pathway
KEGG
INOH
PID NCI
ptp1bpathway
Signaling events mediated by PTP1B
reg_gr_pathway
Glucocorticoid receptor regulatory network
Cross-References
SwissProt P05814
TrEMBL W5RWE1
UniProt Splice Variant
Entrez Gene 1447
UniGene Hs.2242
RefSeq NM_001891 XM_005265647
HUGO HGNC:2447
OMIM 115460
CCDS CCDS3532
HPRD
IMGT
EMBL AF027807 BC069554 BC096194 BC096195 BC096196 BC096197 CH471057 KF751868 X13766 X17070 X55739
GenPept AAC82978 AAH69554 AAH96194 AAH96195 AAH96196 AAH96197 AHG94922 CAA32017 CAA34916 CAA39270 EAX05602
RNA Seq Atlas 1447

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca