Version 5.4
| Homo sapiens Gene: EDDM3B | |||||
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| Summary | |||||
| InnateDB Gene | IDBG-2378.5 | ||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||
| Gene Symbol | EDDM3B | ||||
| Gene Name | epididymal protein 3B | ||||
| Synonyms | |||||
| Species | Homo sapiens | ||||
| Ensembl Gene | ENSG00000181552 | ||||
| Encoded Proteins |
epididymal protein 3B
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||
| Entrez Gene | |||||
| Summary |
Testicular sperm are morphologically differentiated but are not progressively motile nor able to fertilize an egg. Post-testicular maturation requires exposure of spermatozoa to the microenvironment of the epididymal lumen. Spermatozoa undergo extensive changes in the epididymis, including enzymatic modifications, loss of pre-existing components and addition of new glycoproteins from epididymal secretions. These modifying proteins and enzymes are synthesized by epithelial cells lining the epididymal duct and secreted apically into the lumen, where they come into contact with, and may be absorbed onto, the sperm membranes. The proteins encoded by the genes in this cluster are synthesized and secreted by epididymal epithelial cells. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||
| Type | Protein coding | ||||
| Genomic Location | Chromosome 14:20768427-20770948 | ||||
| Strand | Forward strand | ||||
| Band | q11.2 | ||||
| Transcripts |
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| Interactions | |||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||
| No orthologs found for this gene | |||||
| Cross-References | |||||
| SwissProt | P56851 | ||||
| TrEMBL | W0UV31 | ||||
| UniProt Splice Variant | |||||
| Entrez Gene | 64184 | ||||
| UniGene | Hs.525202 | ||||
| RefSeq | NM_022360 | ||||
| HUGO | HGNC:19223 | ||||
| OMIM | 611582 | ||||
| CCDS | CCDS9557 | ||||
| HPRD | |||||
| IMGT | |||||
| EMBL | AY358865 BC128030 CH471078 HG328850 X76386 | ||||
| GenPept | AAI28031 AAQ89224 CAC17141 CDG31926 EAW66443 | ||||
| RNA Seq Atlas | 64184 | ||||