Homo sapiens Gene: RASSF6
Summary
InnateDB Gene IDBG-23874.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RASSF6
Gene Name Ras association (RalGDS/AF-6) domain family member 6
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000169435
Encoded Proteins
Ras association (RalGDS/AF-6) domain family member 6
Ras association (RalGDS/AF-6) domain family member 6
Ras association (RalGDS/AF-6) domain family member 6
Ras association (RalGDS/AF-6) domain family member 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the Ras-association domain family (RASSF). Members of this family form the core of a highly conserved tumor suppressor network, the Salvador-Warts-Hippo (SWH) pathway. The protein encoded by this gene is a Ras effector protein that induces apoptosis. A genomic region containing this gene has been linked to susceptibility to viral bronchiolitis. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:73571550-73620631
Strand Reverse strand
Band q13.3
Transcripts
ENST00000307439 ENSP00000303877
ENST00000342081 ENSP00000340578
ENST00000335049 ENSP00000335582
ENST00000395777 ENSP00000379123
ENST00000512591
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006915 apoptotic process
GO:0007165 signal transduction
GO:0042981 regulation of apoptotic process
GO:0043065 positive regulation of apoptotic process
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt Q6ZTQ3
TrEMBL
UniProt Splice Variant
Entrez Gene 166824
UniGene Hs.529677 Hs.601647 Hs.603193
RefSeq NM_001270391 NM_001270392 NM_177532 NM_201431
HUGO HGNC:20796
OMIM 612620
CCDS CCDS3558 CCDS3559 CCDS58904 CCDS58905
HPRD
IMGT
EMBL AK126346 AY217664 AY217665 BC058835 CR749283
GenPept AAH58835 AAO61689 AAO61690 BAC86530 CAH18138
RNA Seq Atlas 166824