Version 5.4
Homo sapiens Gene: PTPRCAP
Summary
InnateDB Gene IDBG-242684.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PTPRCAP
Gene Name protein tyrosine phosphatase, receptor type, C-associated protein
Synonyms CD45-AP; LPAP
Species Homo sapiens
Ensembl Gene ENSG00000213402
Encoded Proteins
IDBP-60384
protein tyrosine phosphatase, receptor type, C-associated protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene was identified as a transmembrane phosphoprotein specifically associated with tyrosine phosphatase PTPRC/CD45, a key regulator of T- and B-lymphocyte activation. The interaction with PTPRC may be required for the stable expression of this protein. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:67435510-67438067
Strand Reverse strand
Band q13.2
Transcripts
ENST00000326294 ENSP00000325589
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 3 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006952 defense response
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000045826
View Gene Order
ENSBTAG00000004782
Not yet available
Cross-References
SwissProt Q14761
TrEMBL
UniProt Splice Variant
Entrez Gene 5790
UniGene
RefSeq NM_005608
HUGO HGNC:9667
OMIM 601577
CCDS CCDS8163
HPRD 09032
IMGT
EMBL AK312022 BC113859 BC114467 CR457429 X81422 X97267
GenPept AAI13860 AAI14468 BAG34959 CAA57182 CAA65922 CAG33710
RNA Seq Atlas 5790

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca