Version 5.4
Homo sapiens Gene: ACSBG1
Summary
InnateDB Gene IDBG-24518.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACSBG1
Gene Name acyl-CoA synthetase bubblegum family member 1
Synonyms BG; BG1; BGM; GR-LACS; LPD
Species Homo sapiens
Ensembl Gene ENSG00000103740
Encoded Proteins
IDBP-24520
acyl-CoA synthetase bubblegum family member 1
IDBP-598315
acyl-CoA synthetase bubblegum family member 1
IDBP-589660
acyl-CoA synthetase bubblegum family member 1
IDBP-584347
acyl-CoA synthetase bubblegum family member 1
IDBP-591547
acyl-CoA synthetase bubblegum family member 1
IDBP-587922
acyl-CoA synthetase bubblegum family member 1
IDBP-595154
acyl-CoA synthetase bubblegum family member 1
IDBP-592229
acyl-CoA synthetase bubblegum family member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene possesses long-chain acyl-CoA synthetase activity. It is thought to play a central role in brain very long-chain fatty acids metabolism and myelinogenesis. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:78167468-78245688
Strand Reverse strand
Band q25.1
Transcripts
ENST00000258873 ENSP00000258873
ENST00000560124 ENSP00000453605
ENST00000560817 ENSP00000453451
ENST00000560183
ENST00000558301
ENST00000559707 ENSP00000453447
ENST00000558728
ENST00000557935 ENSP00000453585
ENST00000559114 ENSP00000454188
ENST00000559241 ENSP00000453547
ENST00000558130 ENSP00000453800
ENST00000558828
ENST00000558793
ENST00000559713
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004467 long-chain fatty acid-CoA ligase activity
GO:0005524 ATP binding
GO:0031957 very long-chain fatty acid-CoA ligase activity
Biological Process
GO:0000038 very long-chain fatty acid metabolic process
GO:0001552 ovarian follicle atresia
GO:0001676 long-chain fatty acid metabolic process
GO:0008152 metabolic process
GO:0042552 myelination
GO:0051384 response to glucocorticoid
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0016023 cytoplasmic membrane-bounded vesicle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000032281
View Gene Order
ENSBTAG00000006231
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00061
Fatty acid biosynthesis pathway
hsa00071
Fatty acid degradation pathway
hsa03320
PPAR signaling pathway pathway
hsa04920
Adipocytokine signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.595357 Hs.604929 Hs.655760 Hs.659780
RefSeq NM_001199377 NM_015162
HUGO
OMIM
CCDS CCDS10298
HPRD 16549
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca