Version 5.4
Homo sapiens Gene: CERS4
Summary
InnateDB Gene IDBG-24521.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CERS4
Gene Name ceramide synthase 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000090661
Encoded Proteins
IDBP-24523
ceramide synthase 4
IDBP-594551
ceramide synthase 4
IDBP-599005
ceramide synthase 4
IDBP-601999
ceramide synthase 4
IDBP-590655
ceramide synthase 4
IDBP-585904
ceramide synthase 4
IDBP-590427
ceramide synthase 4
IDBP-586023
ceramide synthase 4
IDBP-587440
ceramide synthase 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:8206736-8262421
Strand Forward strand
Band p13.2
Transcripts
ENST00000251363 ENSP00000251363
ENST00000561008 ENSP00000453796
ENST00000558268 ENSP00000453388
ENST00000558331 ENSP00000452753
ENST00000561053 ENSP00000452910
ENST00000559490
ENST00000559450 ENSP00000453509
ENST00000559336 ENSP00000453815
ENST00000558501
ENST00000560412 ENSP00000452920
ENST00000558877 ENSP00000454122
ENST00000557925
ENST00000558302
ENST00000595722
ENST00000599275
ENST00000600912
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0050291 sphingosine N-acyltransferase activity
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006665 sphingolipid metabolic process
GO:0030148 sphingolipid biosynthetic process
GO:0044281 small molecule metabolic process
GO:0046513 ceramide biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
GO:0031965 nuclear membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000008206
View Gene Order
ENSBTAG00000003434
Not yet available
Pathways
NETPATH
REACTOME
REACT_115810
Sphingolipid de novo biosynthesis pathway
REACT_19323
Sphingolipid metabolism pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_111217
Metabolism pathway
KEGG
hsa00600
Sphingolipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL H0YKC9
UniProt Splice Variant
Entrez Gene 79603
UniGene Hs.515111
RefSeq NM_024552 XM_006722887 XM_006722888 XM_006722889 XM_006722890 XM_006722891 XM_006722892 XM_006722893 XM_006722894 XM_006722895 XM_006722896
HUGO HGNC:23747
OMIM 615334
CCDS CCDS12197
HPRD 13962
IMGT
EMBL AC022146
GenPept
RNA Seq Atlas 79603

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca