Version 5.4
Homo sapiens Gene: GOLGA4
Summary
InnateDB Gene IDBG-24855.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GOLGA4
Gene Name golgin A4
Synonyms CRPF46; GCP2; GOLG; MU-RMS-40.18; p230
Species Homo sapiens
Ensembl Gene ENSG00000144674
Encoded Proteins
IDBP-24857
golgin A4
IDBP-24859
golgin A4
IDBP-371309
golgin A4
IDBP-371339
golgin A4
IDBP-371341
golgin A4
IDBP-371351
golgin A4
IDBP-371361
golgin A4
IDBP-807635
golgin A4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This protein has been postulated to play a role in Rab6-regulated membrane-tethering events in the Golgi apparatus. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:37243177-37366751
Strand Forward strand
Band p22.2
Transcripts
ENST00000361924 ENSP00000354486
ENST00000356847 ENSP00000349305
ENST00000435830
ENST00000444882 ENSP00000406894
ENST00000450863 ENSP00000387633
ENST00000429018 ENSP00000403009
ENST00000431105 ENSP00000392907
ENST00000419177
ENST00000437131 ENSP00000405842
ENST00000497537
ENST00000498250
ENST00000617480 ENSP00000478175
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 15 [view]
Protein-Protein 14 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0051020 GTPase binding
Biological Process
GO:0000042 protein targeting to Golgi
GO:0016192 vesicle-mediated transport
GO:0043001 Golgi to plasma membrane protein transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005802 trans-Golgi network
GO:0016020 membrane
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000038708
View Gene Order
ENSBTAG00000016563
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001172713 NM_002078 XM_005265069 XM_005265070 XM_005265071 XM_005265073 XM_005265074 XM_005265075
HUGO
OMIM
CCDS CCDS2666 CCDS54564
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca