Homo sapiens Gene: GOLGA4

Summary
InnateDB Gene IDBG-24855.5
Last Modified 2012-02-14   [Report errors or provide feedback]
Gene Symbol GOLGA4
Gene Name golgin A4
Synonyms GCP2; GOLG; MU-RMS-40.18; p230
Species Homo sapiens
Ensembl Gene ENSG00000144674
Encoded Proteins
IDBP-24857 golgin A4
IDBP-24859 golgin A4
IDBP-371309 golgin A4
IDBP-371339 golgin A4
IDBP-371341 golgin A4
IDBP-371351 golgin A4
IDBP-371361 golgin A4
Entrez Gene
Summary The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This protein has been postulated to play a role in Rab6-regulated membrane-tethering events in the Golgi apparatus. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 3: 37284668-37408242
Strand Forward strand
Band p22.2
Transcripts
ENST00000361924  ENSP00000354486
ENST00000356847  ENSP00000349305
ENST00000435830 
ENST00000444882  ENSP00000406894
ENST00000450863  ENSP00000387633
ENST00000429018  ENSP00000403009
ENST00000431105  ENSP00000392907
ENST00000419177 
ENST00000437131  ENSP00000405842
ENST00000497537 
ENST00000498250 
Interactions
Number of Interactions   This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 19 [view]
Protein‑Protein  18
[view]
Protein‑DNA 1
[view]
Protein‑RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
 
Predicted by orthology
Total [view]
Gene Ontology
Accession GO Term
Molecular Function
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0051020 GTPase binding
Biological Process
GO:0000042 protein targeting to Golgi
GO:0016192 vesicle-mediated transport
GO:0043001 Golgi to plasma membrane protein transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005802 trans-Golgi network
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID Gene Order Method Confidence Comments
ENSMUSG00000038708 Ortholuge SSD Ortholog Ortholog supports species divergence
ENSBTAG00000016563 Not yet available Ortholuge SSD Ortholog Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q13439 
TrEMBL A8K3D5 C9J0Y3 C9JHJ5 E7EVX2 F8W8Q7 H0Y6I0 Q86W71
UniProt Splice Variant
Entrez Gene 2803 
UniGene Hs.344151 Hs.595282
RefSeq NM_001172713  NM_002078 
HUGO 4427 
OMIM 602509
CCDS CCDS2666  CCDS54564 
HPRD 03941
IMGT
EMBL AC097359 AK290550 BC050444 U31906 U41740 X76942 X82834
GenPept AAC50434  AAC51791  AAH50444  BAF83239  CAA54261  CAA58041 
ImmGen GOLGA4 (murine) 
RNA Seq Atlas 2803