Homo sapiens Gene: GOLGA4
Summary
InnateDB Gene IDBG-24855.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol GOLGA4
Gene Name golgin A4
Synonyms GCP2; GOLG; MU-RMS-40.18; p230;
Species Homo sapiens
Ensembl Gene ENSG00000144674
Encoded Proteins
golgin A4
golgin A4
golgin A4
golgin A4
golgin A4
golgin A4
golgin A4
Protein Structure
Entrez Gene
Summary The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This protein has been postulated to play a role in Rab6-regulated membrane-tethering events in the Golgi apparatus. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:37284668-37408242
Strand Forward strand
Band p22.2
Transcripts
ENST00000361924 ENSP00000354486
ENST00000356847 ENSP00000349305
ENST00000435830
ENST00000444882 ENSP00000406894
ENST00000450863 ENSP00000387633
ENST00000429018 ENSP00000403009
ENST00000431105 ENSP00000392907
ENST00000419177
ENST00000437131 ENSP00000405842
ENST00000497537
ENST00000498250
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 19 [view]
Protein-Protein 18 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0051020 GTPase binding
Biological Process
GO:0000042 protein targeting to Golgi
GO:0016192 vesicle-mediated transport
GO:0043001 Golgi to plasma membrane protein transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005802 trans-Golgi network
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q13439
TrEMBL A8K3D5 C9J0Y3 C9JHJ5 E7EVX2 F8W8Q7 H0Y6I0 Q86W71
UniProt Splice Variant
Entrez Gene 2803
UniGene Hs.344151 Hs.595282
RefSeq NM_001172713 NM_002078
HUGO 4427
OMIM 602509
CCDS CCDS2666 CCDS54564
HPRD 03941
IMGT
EMBL AC097359 AK290550 BC050444 U31906 U41740 X76942 X82834
GenPept AAC50434 AAC51791 AAH50444 BAF83239 CAA54261 CAA58041
ImmGen GOLGA4 (murine)
RNA Seq Atlas 2803