Version 5.4
Mus musculus Gene: Muc4
Summary
InnateDB Gene IDBG-250337.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Muc4
Gene Name mucin 4
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000079620
Encoded Proteins
IDBP-154599
mucin 4
IDBP-536049
mucin 4
IDBP-538151
mucin 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface. A large 5' exon encodes at least 15 tandem repeats of 124-126 amino acids. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:32735886-32782391
Strand Forward strand
Band B3
Transcripts
ENSMUST00000096106 ENSMUSP00000093813
ENSMUST00000115119
ENSMUST00000132475 ENSMUSP00000119029
ENSMUST00000142355
ENSMUST00000135753 ENSMUSP00000119154
ENSMUST00000143297
ENSMUST00000149773
ENSMUST00000131419
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0002244 hematopoietic progenitor cell differentiation
GO:0007160 cell-matrix adhesion
Cellular Component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000145113
View Gene Order
ENSBTAG00000014721
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_115835
Termination of O-glycan biosynthesis pathway
REACT_115606
O-linked glycosylation of mucins pathway
REACT_22161
Post-translational protein modification pathway
REACT_200727
O-linked glycosylation pathway
REACT_17015
Metabolism of proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.214599 Mm.484124
RefSeq NM_080457
OMIM
CCDS
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca