Mus musculus Gene: St6galnac4 | |||||||||
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Summary | |||||||||
InnateDB Gene | IDBG-254187.6 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | St6galnac4 | ||||||||
Gene Name | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 | ||||||||
Synonyms | SIAT7-D; Siat7d; ST6GalNAcIV | ||||||||
Species | Mus musculus | ||||||||
Ensembl Gene | ENSMUSG00000079442 | ||||||||
Encoded Proteins |
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
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Protein Structure | |||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||
Entrez Gene | |||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136840:
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein prefers glycoproteins rather than glycolipids as substrates and shows restricted substrate specificity, utilizing only the trisaccharide sequence Neu5Ac-alpha-2,3-Gal-beta-1,3-GalNAc. In addition, it is involved in the synthesis of ganglioside GD1A from GM1B. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||
Type | Protein coding | ||||||||
Genomic Location | Chromosome 2:32587095-32599698 | ||||||||
Strand | Forward strand | ||||||||
Band | B | ||||||||
Transcripts |
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Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||
NETPATH | |||||||||
REACTOME | |||||||||
KEGG |
Glycosphingolipid biosynthesis pathway
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INOH | |||||||||
PID NCI | |||||||||
Pathway Predictions based on Human Orthology Data | |||||||||
NETPATH | |||||||||
REACTOME |
Termination of O-glycan biosynthesis pathway
O-linked glycosylation of mucins pathway
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Asparagine N-linked glycosylation pathway
Post-translational protein modification pathway
Synthesis of substrates in N-glycan biosythesis pathway
O-linked glycosylation pathway
Sialic acid metabolism pathway
Metabolism of proteins pathway
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KEGG |
Glycosphingolipid biosynthesis pathway
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INOH | |||||||||
PID NCI | |||||||||
Cross-References | |||||||||
SwissProt | |||||||||
TrEMBL | |||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | |||||||||
UniGene | Mm.27446 Mm.488683 | ||||||||
RefSeq | NM_001276425 NM_011373 | ||||||||
OMIM | |||||||||
CCDS | CCDS15921 | ||||||||
HPRD | |||||||||
IMGT | |||||||||
MGI ID | |||||||||
MGI Symbol | |||||||||
EMBL | |||||||||
GenPept | |||||||||
RNA Seq Atlas | |||||||||