Version 5.4
Homo sapiens Gene: GTPBP10
Summary
InnateDB Gene IDBG-25756.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GTPBP10
Gene Name GTP-binding protein 10 (putative)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000105793
Encoded Proteins
IDBP-25758
GTP-binding protein 10 (putative)
IDBP-25760
GTP-binding protein 10 (putative)
IDBP-25762
GTP-binding protein 10 (putative)
IDBP-381346
GTP-binding protein 10 (putative)
IDBP-381351
GTP-binding protein 10 (putative)
IDBP-381353
GTP-binding protein 10 (putative)
IDBP-381355
GTP-binding protein 10 (putative)
IDBP-381359
GTP-binding protein 10 (putative)
IDBP-381361
GTP-binding protein 10 (putative)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Small G proteins, such as GTPBP10, act as molecular switches that play crucial roles in the regulation of fundamental cellular processes such as protein synthesis, nuclear transport, membrane trafficking, and signal transduction (Hirano et al., 2006 [PubMed 17054726]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:90335223-90391455
Strand Forward strand
Band q21.13
Transcripts
ENST00000222511 ENSP00000222511
ENST00000257659 ENSP00000257659
ENST00000380058 ENSP00000369398
ENST00000453512 ENSP00000410311
ENST00000426366 ENSP00000405697
ENST00000450619 ENSP00000389510
ENST00000421719 ENSP00000411091
ENST00000417207 ENSP00000416596
ENST00000439832 ENSP00000416713
ENST00000469675
ENST00000477972
ENST00000474503
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0015093 ferrous iron transmembrane transporter activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006184 GTP catabolic process
GO:0015684 ferrous iron transport
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000040464
View Gene Order
ENSBTAG00000032166
Not yet available
Cross-References
SwissProt A4D1E9
TrEMBL
UniProt Splice Variant
Entrez Gene 85865
UniGene Hs.627110 Hs.641349 Hs.709271 Hs.734999
RefSeq NM_001042717 NM_033107
HUGO HGNC:25106
OMIM 610920
CCDS CCDS43614 CCDS5617
HPRD 14262
IMGT
EMBL AC002064 AC006153 AF351613 AK095561 AK294325 BC004923 BC021573 BC107714 CH236949 CH471091 CR933597
GenPept AAD15550 AAH04923 AAH21573 AAI07715 AAN76513 BAC04573 BAG57597 CAI45922 EAL24164 EAW76880 EAW76882
RNA Seq Atlas 101927446 85865

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca