Version 5.4
Mus musculus Gene: Gzmc
Summary
InnateDB Gene IDBG-258415.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gzmc
Gene Name granzyme C
Synonyms AI323531; CCP2; Ctla-5; Ctla5
Species Mus musculus
Ensembl Gene ENSMUSG00000079186
Encoded Proteins
IDBP-166918
granzyme C
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 14:56231401-56234656
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000015585 ENSMUSP00000015585
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0008626 granzyme-mediated apoptotic signaling pathway
GO:0019835 cytolysis
Cellular Component
GO:0030141 secretory granule
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_258521
Apoptosis pathway
REACT_208000
Activation, myristolyation of BID and translocation to mitochondria pathway
REACT_204001
Intrinsic Pathway for Apoptosis pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt P08882
TrEMBL Q0VB76
UniProt Splice Variant
Entrez Gene 14940
UniGene Mm.14465
RefSeq NM_010371 XM_006518568
OMIM
CCDS CCDS27146
HPRD
IMGT
MGI ID MGI:109256
MGI Symbol Gzmc
EMBL BC120755 BC120757 BC145030 CH466535 M12301 M18459 M22527 X12822
GenPept AAA37384 AAA37734 AAA85454 AAI20756 AAI20758 AAI45031 CAA31309 EDL36203
RNA Seq Atlas 14940

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca