Version 5.4
Homo sapiens Gene: XYLB
Summary
InnateDB Gene IDBG-25894.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol XYLB
Gene Name xylulokinase homolog (H. influenzae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000093217
Encoded Proteins
IDBP-25896
xylulokinase homolog (H. influenzae)
IDBP-372088
xylulokinase homolog (H. influenzae)
IDBP-372100
xylulokinase homolog (H. influenzae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene shares 22% sequence identity with Hemophilus influenzae xylulokinase, and even higher identity to other gene products in C.elegans (45%) and yeast (31-35%), which are thought to belong to a family of enzymes that include fucokinase, gluconokinase, glycerokinase and xylulokinase. These proteins play important roles in energy metabolism. [provided by RefSeq, Aug 2009]
The protein encoded by this gene shares 22%% sequence identity with Hemophilus influenzae xylulokinase, and even higher identity to other gene products in C.elegans (45%%) and yeast (31-35%%), which are thought to belong to a family of enzymes that include fucokinase, gluconokinase, glycerokinase and xylulokinase. These proteins play important roles in energy metabolism. [provided by RefSeq, Aug 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:38346760-38421348
Strand Forward strand
Band p22.2
Transcripts
ENST00000207870 ENSP00000207870
ENST00000427323 ENSP00000412282
ENST00000424034 ENSP00000398845
ENST00000487569
ENST00000472721
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004856 xylulokinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016773 phosphotransferase activity, alcohol group as acceptor
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0005997 xylulose metabolic process
GO:0005998 xylulose catabolic process
GO:0006091 generation of precursor metabolites and energy
GO:0016310 phosphorylation
GO:0042732 D-xylose metabolic process
GO:0046835 carbohydrate phosphorylation
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000035769
View Gene Order
ENSBTAG00000011278
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00040
Pentose and glucuronate interconversions pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.659985
RefSeq NM_005108 XM_006713448 XM_006713449 XM_006713450
HUGO
OMIM
CCDS CCDS2678
HPRD 06812
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca