Version 5.4
| Homo sapiens Gene: GSTT2B | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-2642.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | GSTT2B | ||||||||
| Gene Name | glutathione S-transferase theta 2B (gene/pseudogene) | ||||||||
| Synonyms | |||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Gene | ENSG00000133433 | ||||||||
| Encoded Proteins |
glutathione S-transferase theta 2B (gene/pseudogene)
glutathione S-transferase theta 2B (gene/pseudogene)
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
Glutathione S-transferase (GSTs) theta 2 (GSTT2) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: Alpha, Mu, Pi, Theta, and Zeta. The theta class members GSTT1 and GSTT2 share 55% amino acid sequence identity and both are thought to have an important role in human carcinogenesis. The theta genes have a similar structure, being composed of five exons with identical exon/intron boundaries. [provided by RefSeq, Jul 2008] Glutathione S-transferase (GSTs) theta 2 (GSTT2) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: Alpha, Mu, Pi, Theta, and Zeta. The theta class members GSTT1 and GSTT2 share 55%% amino acid sequence identity and both are thought to have an important role in human carcinogenesis. The theta genes have a similar structure, being composed of five exons with identical exon/intron boundaries. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 22:23957414-23961186 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | q11.23 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
| No orthologs found for this gene | |||||||||
| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Glutathione conjugation pathway
Phase II conjugation pathway
Metabolism pathway
Biological oxidations pathway
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| KEGG |
Glutathione metabolism pathway
Metabolism of xenobiotics by cytochrome P450 pathway
Drug metabolism pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | P0CG30 | ||||||||
| TrEMBL | G9J6Q5 Q6ICJ4 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 653689 | ||||||||
| UniGene | Hs.656498 | ||||||||
| RefSeq | NM_001080843 XM_005261590 XM_005261715 XM_006725408 | ||||||||
| HUGO | HGNC:33437 | ||||||||
| OMIM | 600437 | ||||||||
| CCDS | CCDS33617 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AF057173 AF057174 AF057175 AF057176 AP000350 BC002415 BC146940 BC146943 CH471095 CR456374 CR456500 JN819428 L38503 | ||||||||
| GenPept | AAB63956 AAC13317 AAH02415 AAI46941 AAI46944 AEW26631 CAG30260 CAG30386 EAW59625 EAW59626 | ||||||||
| RNA Seq Atlas | 2953 653689 | ||||||||