Version 5.4
Homo sapiens Gene: RAB2B
Summary
InnateDB Gene IDBG-2666.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RAB2B
Gene Name RAB2B, member RAS oncogene family
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000129472
Encoded Proteins
IDBP-234622
RAB2B, member RAS oncogene family
IDBP-361130
RAB2B, member RAS oncogene family
IDBP-811303
RAB2B, member RAS oncogene family
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rab proteins are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking; see MIM 179508.[supplied by OMIM, Apr 2006]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:21459020-21476973
Strand Reverse strand
Band q11.2
Transcripts
ENST00000397762 ENSP00000380869
ENST00000417141 ENSP00000405441
ENST00000461909
ENST00000475857
ENST00000485996
ENST00000622293 ENSP00000484914
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0006913 nucleocytoplasmic transport
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
GO:0045921 positive regulation of exocytosis
Cellular Component
GO:0000139 Golgi membrane
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022159
View Gene Order
ENSBTAG00000044207
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001163380 NM_032846
HUGO
OMIM
CCDS CCDS9570
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca