Version 5.4
Homo sapiens Gene: KIF21A
Summary
InnateDB Gene IDBG-26836.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KIF21A
Gene Name kinesin family member 21A
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000139116
Encoded Proteins
IDBP-26838
kinesin family member 21A
IDBP-26840
kinesin family member 21A
IDBP-601237
kinesin family member 21A
IDBP-589490
kinesin family member 21A
IDBP-584770
kinesin family member 21A
IDBP-587492
kinesin family member 21A
IDBP-586407
kinesin family member 21A
IDBP-597251
kinesin family member 21A
IDBP-583677
kinesin family member 21A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the KIF4 subfamily of kinesin-like motor proteins. The encoded protein is characterized by an N-terminal motor domain a coiled-coil stalk domain and a C-terminal WD-40 repeat domain. This protein may be involved in microtubule dependent transport. Mutations in this gene are the cause of congenital fibrosis of extraocular muscles-1. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:39293228-39443390
Strand Reverse strand
Band q12
Transcripts
ENST00000361961 ENSP00000354851
ENST00000361418 ENSP00000354878
ENST00000547733
ENST00000551264 ENSP00000448792
ENST00000552961 ENSP00000447765
ENST00000544797 ENSP00000445606
ENST00000541463 ENSP00000438075
ENST00000547745
ENST00000547108 ENSP00000449698
ENST00000552475
ENST00000551066 ENSP00000447070
ENST00000546817
ENST00000550429
ENST00000552908 ENSP00000449700
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003777 microtubule motor activity
GO:0005488 binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement
GO:0008152 metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005871 kinesin complex
GO:0005874 microtubule
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022629
View Gene Order
ENSBTAG00000004832
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.374201
RefSeq NM_001173463 NM_001173464 NM_001173465 NM_017641 XM_005269007 XM_005269008 XM_005269009 XM_005269010 XM_005269012 XM_005269013 XM_006719493 XM_006719494 XM_006719495 XM_006719496
HUGO
OMIM
CCDS CCDS31773 CCDS53774 CCDS53775 CCDS53776
HPRD 10506
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca