Version 5.4
Homo sapiens Gene: WBP4
Summary
InnateDB Gene IDBG-27004.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WBP4
Gene Name WW domain binding protein 4
Synonyms FBP21
Species Homo sapiens
Ensembl Gene ENSG00000120688
Encoded Proteins
IDBP-27006
WW domain binding protein 4 (formin binding protein 21)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes WW domain-containing binding protein 4. The WW domain represents a small and compact globular structure that interacts with proline-rich ligands. This encoded protein is a general spliceosomal protein that may play a role in cross-intron bridging of U1 and U2 snRNPs in the spliceosomal complex A. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:41061274-41084006
Strand Forward strand
Band q14.11
Transcripts
ENST00000379487 ENSP00000368801
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 87 experimentally validated interaction(s) in this database.
Experimentally validated
Total 87 [view]
Protein-Protein 85 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0070064 proline-rich region binding
Biological Process
GO:0045292 mRNA cis splicing, via spliceosome
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005886 plasma membrane
GO:0016607 nuclear speck
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022023
View Gene Order
ENSBTAG00000016637
Not yet available
Cross-References
SwissProt O75554
TrEMBL B7Z4M2
UniProt Splice Variant
Entrez Gene 11193
UniGene Hs.411300 Hs.595899
RefSeq NM_007187 XM_005266245
HUGO HGNC:12739
OMIM 604981
CCDS CCDS9375
HPRD
IMGT
EMBL AF071185 AK297536 AL157877 BC104879 BC108310
GenPept AAC34811 AAI04880 AAI08311 BAH12608 CAI13223
RNA Seq Atlas 11193

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca