Version 5.4
Homo sapiens Gene: SH3GL3
Summary
InnateDB Gene IDBG-27199.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SH3GL3
Gene Name SH3-domain GRB2-like 3
Synonyms CNSA3; EEN-B2; HsT19371; SH3D2C; SH3P13
Species Homo sapiens
Ensembl Gene ENSG00000140600
Encoded Proteins
IDBP-27201
SH3-domain GRB2-like 3
IDBP-379417
SH3-domain GRB2-like 3
IDBP-746890
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 15:83447228-83618743
Strand Forward strand
Band q25.2
Transcripts
ENST00000324537 ENSP00000320092
ENST00000427482 ENSP00000391372
ENST00000492099
ENST00000467735
ENST00000563901 ENSP00000456249
ENST00000564054
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 60 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 60 [view]
Protein-Protein 60 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008289 lipid binding
GO:0042802 identical protein binding
Biological Process
GO:0006897 endocytosis
GO:0007165 signal transduction
GO:0007417 central nervous system development
Cellular Component
GO:0005737 cytoplasm
GO:0031901 early endosome membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030638
View Gene Order
ENSBTAG00000018004
Not yet available
Pathways
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
hsa04144
Endocytosis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.270055 Hs.599441
RefSeq NM_001301108 NM_001301109 NM_003027 XM_006720638
HUGO
OMIM
CCDS CCDS10325 CCDS73772
HPRD 04528
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca