Version 5.4
| Homo sapiens Gene: MTRF1 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-27238.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | MTRF1 | ||||||||||||||||||
| Gene Name | mitochondrial translational release factor 1 | ||||||||||||||||||
| Synonyms | MRF1; MTTRF1; RF1 | ||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000120662 | ||||||||||||||||||
| Encoded Proteins |
mitochondrial translational release factor 1
mitochondrial translational release factor 1
mitochondrial translational release factor 1
mitochondrial translational release factor 1
mitochondrial translational release factor 1
mitochondrial translational release factor 1
mitochondrial translational release factor 1
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
The protein encoded by this gene was determined by in silico methods to be a mitochondrial protein with similarity to the peptide chain release factors (RFs) discovered in bacteria and yeast. The peptide chain release factors direct the termination of translation in response to the peptide chain termination codons. Initially thought to have a role in the termination of mitochondria protein synthesis, a recent publication found no mitochondrial translation release functionality. Multiple alternatively spliced transcript variants have been suggested by mRNA and EST data; however, their full-length natures are not clear. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 13:41216369-41263577 | ||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||
| Band | q14.11 | ||||||||||||||||||
| Transcripts | |||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
Organelle biogenesis and maintenance pathway
Mitochondrial translation pathway
Mitochondrial translation termination pathway
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| KEGG | |||||||||||||||||||
| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | O75570 | ||||||||||||||||||
| TrEMBL | A0A024RDT1 Q8N6Z2 X6RFD4 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 9617 | ||||||||||||||||||
| UniGene | Hs.737057 | ||||||||||||||||||
| RefSeq | NM_004294 XM_005266599 XM_006719897 XM_006719898 XM_006719899 XM_006719900 XM_006719901 | ||||||||||||||||||
| HUGO | HGNC:7469 | ||||||||||||||||||
| OMIM | 604601 | ||||||||||||||||||
| CCDS | CCDS9378 | ||||||||||||||||||
| HPRD | |||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AF072934 AL354696 BC027731 BC042196 CH471075 | ||||||||||||||||||
| GenPept | AAD12759 AAH27731 AAH42196 CAI16615 CAI16617 EAX08648 EAX08649 EAX08650 EAX08651 EAX08653 | ||||||||||||||||||
| RNA Seq Atlas | 9617 | ||||||||||||||||||