Version 5.4
Homo sapiens Gene: PPP1R9A
Summary
InnateDB Gene IDBG-27622.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPP1R9A
Gene Name protein phosphatase 1, regulatory subunit 9A
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000158528
Encoded Proteins
IDBP-27624
protein phosphatase 1, regulatory subunit 9A
IDBP-27626
protein phosphatase 1, regulatory subunit 9A
IDBP-382220
protein phosphatase 1, regulatory subunit 9A
IDBP-382225
protein phosphatase 1, regulatory subunit 9A
IDBP-382226
protein phosphatase 1, regulatory subunit 9A
IDBP-382227
protein phosphatase 1, regulatory subunit 9A
IDBP-382229
protein phosphatase 1, regulatory subunit 9A
IDBP-382231
protein phosphatase 1, regulatory subunit 9A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is imprinted, and located in a cluster of imprinted genes on chromosome 7q12. This gene is transcribed in both neuronal and multiple embryonic tissues, and it is maternally expressed mainly in embryonic skeletal muscle tissues and biallelically expressed in other embryonic tissues. The protein encoded by this gene includes a PDZ domain and a sterile alpha motif (SAM). It is a regulatory subunit of protein phosphatase I, and controls actin cytoskeleton reorganization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:94907202-95296415
Strand Forward strand
Band q21.3
Transcripts
ENST00000340694 ENSP00000344524
ENST00000289495 ENSP00000289495
ENST00000413325 ENSP00000405820
ENST00000433360 ENSP00000405514
ENST00000424654 ENSP00000411342
ENST00000422324 ENSP00000398499
ENST00000433881 ENSP00000398870
ENST00000456331 ENSP00000402893
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0051015 actin filament binding
Biological Process
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007015 actin filament organization
GO:0019722 calcium-mediated signaling
GO:0031175 neuron projection development
Cellular Component
GO:0005739 mitochondrion
GO:0005856 cytoskeleton
GO:0030054 cell junction
GO:0030175 filopodium
GO:0030426 growth cone
GO:0030864 cortical actin cytoskeleton
GO:0043197 dendritic spine
GO:0045202 synapse
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000032827
View Gene Order
ENSBTAG00000024426
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.633210
RefSeq NM_001166160 NM_001166161 NM_001166162 NM_001166163 NM_017650
HUGO
OMIM
CCDS CCDS34683 CCDS55127 CCDS55128
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca