Version 5.4
| Homo sapiens Gene: PSG3 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-281677.5 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | PSG3 | ||||||||||||||||||
| Gene Name | pregnancy specific beta-1-glycoprotein 3 | ||||||||||||||||||
| Synonyms | |||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000221826 | ||||||||||||||||||
| Encoded Proteins |
pregnancy specific beta-1-glycoprotein 3
pregnancy specific beta-1-glycoprotein 3
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 [PubMed 7851896]). For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 19:42721638-42740569 | ||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||
| Band | q13.2 | ||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
| No orthologs found for this gene | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | Q16557 | ||||||||||||||||||
| TrEMBL | |||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 5671 | ||||||||||||||||||
| UniGene | Hs.654413 | ||||||||||||||||||
| RefSeq | NM_021016 | ||||||||||||||||||
| HUGO | HGNC:9520 | ||||||||||||||||||
| OMIM | 176392 | ||||||||||||||||||
| CCDS | CCDS12611 | ||||||||||||||||||
| HPRD | 08892 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AC004654 AC005337 AH007624 BC005924 M23575 M34420 M37399 M93061 S59493 | ||||||||||||||||||
| GenPept | AAA52606 AAA52607 AAA60207 AAA60958 AAC15513 AAC60584 AAD28498 AAH05924 | ||||||||||||||||||
| RNA Seq Atlas | 5671 | ||||||||||||||||||