Version 5.4
Homo sapiens Gene: NELL2
Summary
InnateDB Gene IDBG-28191.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NELL2
Gene Name NEL-like 2 (chicken)
Synonyms NRP2
Species Homo sapiens
Ensembl Gene ENSG00000184613
Encoded Proteins
IDBP-28193
NEL-like 2 (chicken)
IDBP-239435
NEL-like 2 (chicken)
IDBP-372829
NEL-like 2 (chicken)
IDBP-372830
NEL-like 2 (chicken)
IDBP-372833
NEL-like 2 (chicken)
IDBP-603980
NEL-like 2 (chicken)
IDBP-583999
NEL-like 2 (chicken)
IDBP-600228
NEL-like 2 (chicken)
IDBP-593062
NEL-like 2 (chicken)
IDBP-599376
NEL-like 2 (chicken)
IDBP-602246
NEL-like 2 (chicken)
IDBP-592512
NEL-like 2 (chicken)
IDBP-594991
NEL-like 2 (chicken)
IDBP-596222
NEL-like 2 (chicken)
IDBP-598926
NEL-like 2 (chicken)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a glycoprotein containing several von Willebrand factor C domains and epidermal growth factor (EGF)-like domains. The encoded protein acts as a homotrimer and is found in the cytoplasm. Several variants encoding a few different isoforms exist, and at least one isoform appears to be a secreted protein. Studies in mouse suggest that this protein plays a role in neural cell growth and differentiation as well as in oncogenesis. [provided by RefSeq, Feb 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:44508275-44921848
Strand Reverse strand
Band q12
Transcripts
ENST00000333837 ENSP00000327988
ENST00000395487 ENSP00000378866
ENST00000437801 ENSP00000416341
ENST00000452445 ENSP00000394612
ENST00000429094 ENSP00000390680
ENST00000551601 ENSP00000449332
ENST00000549027 ENSP00000447927
ENST00000547636
ENST00000550139 ENSP00000448107
ENST00000549668
ENST00000550313 ENSP00000448407
ENST00000547751
ENST00000550462 ENSP00000450102
ENST00000552993 ENSP00000447085
ENST00000547172
ENST00000553120 ENSP00000447384
ENST00000548826 ENSP00000448635
ENST00000548531 ENSP00000449068
ENST00000546415
ENST00000551949 ENSP00000446961
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 8 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005576 extracellular region
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022454
View Gene Order
ENSBTAG00000032183
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.505326
RefSeq NM_001145107 NM_001145108 NM_001145109 NM_001145110 NM_006159 XM_005268905
HUGO
OMIM
CCDS CCDS44863 CCDS44864 CCDS53781 CCDS8746
HPRD 11891
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca