Homo sapiens Gene: AKAP11
Summary
InnateDB Gene IDBG-28250.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AKAP11
Gene Name A kinase (PRKA) anchor protein 11
Synonyms AKAP-11; AKAP220; PPP1R44; PRKA11
Species Homo sapiens
Ensembl Gene ENSG00000023516
Encoded Proteins
A kinase (PRKA) anchor protein 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed at high levels throughout spermatogenesis and in mature sperm. It binds the RI and RII subunits of PKA in testis. It may serve a function in cell cycle control of both somatic cells and germ cells in addition to its putative role in spermatogenesis and sperm function. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:42272153-42323267
Strand Forward strand
Band q14.11
Transcripts
ENST00000025301 ENSP00000025301
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008157 protein phosphatase 1 binding
GO:0051018 protein kinase A binding
Biological Process
GO:0035556 intracellular signal transduction
Cellular Component
GO:0005737 cytoplasm
GO:0005815 microtubule organizing center
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt Q9UKA4
TrEMBL Q6AI61
UniProt Splice Variant
Entrez Gene 11215
UniGene Hs.105105 Hs.601805 Hs.703132
RefSeq NM_016248 XM_005266248 XM_005266249 XM_005266250
HUGO HGNC:369
OMIM 604696
CCDS CCDS9383
HPRD
IMGT
EMBL AB014529 AF176555 AK002166 AL136527 CR627087
GenPept AAF07045 BAA31604 BAA92117 CAB89419 CAH10362
RNA Seq Atlas 11215