Version 5.4
Homo sapiens Gene: MATN2
Summary
InnateDB Gene IDBG-29765.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MATN2
Gene Name matrilin 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000132561
Encoded Proteins
IDBP-29767
matrilin 2
IDBP-482978
matrilin 2
IDBP-479894
matrilin 2
IDBP-475992
matrilin 2
IDBP-479100
matrilin 2
IDBP-476937
matrilin 2
IDBP-476445
matrilin 2
IDBP-481895
matrilin 2
IDBP-479121
matrilin 2
IDBP-482684
matrilin 2
IDBP-480171
matrilin 2
IDBP-474701
matrilin 2
IDBP-485109
matrilin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the von Willebrand factor A domain containing protein family. This family of proteins is thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This protein contains five von Willebrand factor A domains. The specific function of this gene has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:97868840-98036716
Strand Forward strand
Band q22.1
Transcripts
ENST00000254898 ENSP00000254898
ENST00000521689 ENSP00000429977
ENST00000524308 ENSP00000430221
ENST00000523490
ENST00000522025 ENSP00000429010
ENST00000520160
ENST00000520016 ENSP00000430487
ENST00000518154 ENSP00000429622
ENST00000521041 ENSP00000430396
ENST00000519585 ENSP00000429042
ENST00000518238
ENST00000522270 ENSP00000429825
ENST00000521952 ENSP00000429256
ENST00000517321 ENSP00000429885
ENST00000518370
ENST00000519582 ENSP00000430358
ENST00000523561
ENST00000522135 ENSP00000429354
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0001764 neuron migration
GO:0007411 axon guidance
GO:0008150 biological_process
GO:0008347 glial cell migration
GO:0031104 dendrite regeneration
GO:0031175 neuron projection development
GO:0048678 response to axon injury
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0005604 basement membrane
GO:0031012 extracellular matrix
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022324
View Gene Order
ENSBTAG00000017165
Not yet available
Cross-References
SwissProt O00339
TrEMBL E5RJM4 H0YBM3 J3KN08
UniProt Splice Variant
Entrez Gene 4147
UniGene Hs.668456
RefSeq NM_002380 NM_030583
HUGO HGNC:6908
OMIM 602108
CCDS CCDS55264 CCDS55265
HPRD
IMGT
EMBL AK289721 AL137638 AL833931 AP002906 AP003352 AY358895 BC010444 BC016394 U69263
GenPept AAC51260 AAH10444 AAH16394 AAQ89254 BAF82410 CAB70853 CAD38787
RNA Seq Atlas 100506558 4147

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca