Version 5.4
Homo sapiens Gene: PPFIBP2
Summary
InnateDB Gene IDBG-30119.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPFIBP2
Gene Name PTPRF interacting protein, binding protein 2 (liprin beta 2)
Synonyms Cclp1
Species Homo sapiens
Ensembl Gene ENSG00000166387
Encoded Proteins
IDBP-30121
PTPRF interacting protein, binding protein 2 (liprin beta 2)
IDBP-593909
PTPRF interacting protein, binding protein 2 (liprin beta 2)
IDBP-597133
PTPRF interacting protein, binding protein 2 (liprin beta 2)
IDBP-588524
PTPRF interacting protein, binding protein 2 (liprin beta 2)
IDBP-586433
PTPRF interacting protein, binding protein 2 (liprin beta 2)
IDBP-596047
PTPRF interacting protein, binding protein 2 (liprin beta 2)
IDBP-588307
PTPRF interacting protein, binding protein 2 (liprin beta 2)
IDBP-584472
PTPRF interacting protein, binding protein 2 (liprin beta 2)
IDBP-585718
PTPRF interacting protein, binding protein 2 (liprin beta 2)
IDBP-594207
PTPRF interacting protein, binding protein 2 (liprin beta 2)
IDBP-584575
PTPRF interacting protein, binding protein 2 (liprin beta 2)
IDBP-596448
PTPRF interacting protein, binding protein 2 (liprin beta 2)
IDBP-586036
PTPRF interacting protein, binding protein 2 (liprin beta 2)
IDBP-592397
PTPRF interacting protein, binding protein 2 (liprin beta 2)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. The encoded protein is a beta liprin and plays a role in axon guidance and neuronal synapse development by recruiting LAR protein-tyrosine phosphatases to the plasma membrane. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:7513298-7657127
Strand Forward strand
Band p15.4
Transcripts
ENST00000299492 ENSP00000299492
ENST00000526873 ENSP00000434641
ENST00000528947 ENSP00000431724
ENST00000527790 ENSP00000434981
ENST00000526046 ENSP00000433026
ENST00000524548 ENSP00000433917
ENST00000529575 ENSP00000435794
ENST00000533792 ENSP00000436498
ENST00000532926
ENST00000525597 ENSP00000433839
ENST00000529021
ENST00000528883 ENSP00000435469
ENST00000529321
ENST00000530189
ENST00000530181 ENSP00000437321
ENST00000532416
ENST00000534409 ENSP00000433713
ENST00000530582
ENST00000532381
ENST00000530081 ENSP00000436739
ENST00000532172
ENST00000524495
ENST00000532112
ENST00000528929
ENST00000529664
ENST00000534552 ENSP00000436489
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008907 integrase activity
Biological Process
GO:0015074 DNA integration
Cellular Component
GO:0005615 extracellular space
GO:0005622 intracellular
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036528
View Gene Order
ENSBTAG00000016140
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.655714 Hs.738406 Hs.739217 Hs.740974
RefSeq NM_001256568 NM_001256569 NM_003621
HUGO
OMIM
CCDS CCDS31419 CCDS58116 CCDS58117
HPRD 04391
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca