Homo sapiens Gene: RPS28
Summary
InnateDB Gene IDBG-301310.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RPS28
Gene Name ribosomal protein S28
Synonyms S28
Species Homo sapiens
Ensembl Gene ENSG00000233927
Encoded Proteins
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S28E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:8321158-8323340
Strand Forward strand
Band p13.2
Transcripts
ENST00000417088
ENST00000449223
ENST00000602140
ENST00000600659 ENSP00000472469
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 107 experimentally validated interaction(s) in this database.
Experimentally validated
Total 107 [view]
Protein-Protein 103 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 3 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003735 structural constituent of ribosome
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0006364 rRNA processing
GO:0006412 translation
GO:0006413 translational initiation
GO:0006414 translational elongation
GO:0006415 translational termination
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0010467 gene expression
GO:0016032 viral process
GO:0016070 RNA metabolic process
GO:0016071 mRNA metabolic process
GO:0019058 viral life cycle
GO:0019083 viral transcription
GO:0042274 ribosomal small subunit biogenesis
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:0070062 extracellular vesicular exosome
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
L13a-mediated translational silencing of Ceruloplasmin expression pathway
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
Translation initiation complex formation pathway
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S pathway
Formation of a pool of free 40S subunits pathway
Formation of the ternary complex, and subsequently, the 43S complex pathway
Ribosomal scanning and start codon recognition pathway
Eukaryotic Translation Termination pathway
Peptide chain elongation pathway
Eukaryotic Translation Elongation pathway
SRP-dependent cotranslational protein targeting to membrane pathway
Viral mRNA Translation pathway
Eukaryotic Translation Initiation pathway
Influenza Infection pathway
Nonsense-Mediated Decay (NMD) pathway
Influenza Viral RNA Transcription and Replication pathway
Translation pathway
Metabolism of proteins pathway
Cap-dependent Translation Initiation pathway
Influenza Life Cycle pathway
Gene Expression pathway
Disease pathway
KEGG
Ribosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001031
HUGO
OMIM
CCDS CCDS45953
HPRD 04731
IMGT
EMBL
GenPept
RNA Seq Atlas