Homo sapiens Gene: DDX23 | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-30453.6 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | DDX23 | ||||||||||||||||||
Gene Name | DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 | ||||||||||||||||||
Synonyms | prp28; PRPF28; SNRNP100; U5-100K; U5-100KD | ||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||
Ensembl Gene | ENSG00000174243 | ||||||||||||||||||
Encoded Proteins |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
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Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 12:48829764-48852842 | ||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||
Band | q13.12 | ||||||||||||||||||
Transcripts | |||||||||||||||||||
Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 39 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||
NETPATH | |||||||||||||||||||
REACTOME |
mRNA Splicing - Major Pathway pathway
mRNA Splicing - Minor Pathway pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
mRNA Splicing pathway
Gene Expression pathway
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KEGG |
Spliceosome pathway
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INOH | |||||||||||||||||||
PID NCI | |||||||||||||||||||
Cross-References | |||||||||||||||||||
SwissProt | |||||||||||||||||||
TrEMBL | H0YIL9 | ||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | 9416 | ||||||||||||||||||
UniGene | Hs.130098 | ||||||||||||||||||
RefSeq | NM_004818 XM_006719699 | ||||||||||||||||||
HUGO | HGNC:17347 | ||||||||||||||||||
OMIM | 612172 | ||||||||||||||||||
CCDS | CCDS8770 | ||||||||||||||||||
HPRD | 09908 | ||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | AC117498 | ||||||||||||||||||
GenPept | |||||||||||||||||||
RNA Seq Atlas | 9416 | ||||||||||||||||||