Homo sapiens Gene: KLLN
Summary
InnateDB Gene IDBG-306974.3
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol KLLN
Gene Name killin, p53-regulated DNA replication inhibitor
Synonyms CWS4; KILLIN;
Species Homo sapiens
Ensembl Gene ENSG00000227268
Encoded Proteins
killin, p53-regulated DNA replication inhibitor
Protein Structure
Entrez Gene
Summary The protein encoded by this intronless gene is found in the nucleus, where it can inhibit DNA synthesis and promote S phase arrest coupled to apoptosis. The expression of this DNA binding protein is upregulated by transcription factor p53. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:89618918-89623194
Strand Reverse strand
Band q23.31
Transcripts
ENST00000445946 ENSP00000392204
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
Biological Process
GO:0006915 apoptotic process
GO:0007049 cell cycle
Cellular Component
GO:0005634 nucleus
Orthologs
No orthologs found for this gene
Cross-References
SwissProt B2CW77
TrEMBL
UniProt Splice Variant
Entrez Gene 100144748
UniGene Hs.313888 Hs.559820
RefSeq NM_001126049
HUGO 37212
OMIM 612105
CCDS CCDS44454
HPRD
IMGT
EMBL AC063965 EU552092
GenPept ACB45456
ImmGen KLLN (murine)
RNA Seq Atlas 100144748