Homo sapiens Gene: KLLN
Summary
InnateDB Gene IDBG-306974.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KLLN
Gene Name killin, p53-regulated DNA replication inhibitor
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000227268
Encoded Proteins
killin, p53-regulated DNA replication inhibitor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this intronless gene is found in the nucleus, where it can inhibit DNA synthesis and promote S phase arrest coupled to apoptosis. The expression of this DNA binding protein is upregulated by transcription factor p53. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:87859161-87863437
Strand Reverse strand
Band q23.31
Transcripts
ENST00000445946 ENSP00000392204
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
Biological Process
GO:0006915 apoptotic process
GO:0007049 cell cycle
Cellular Component
GO:0005634 nucleus
Orthologs
No orthologs found for this gene
Cross-References
SwissProt B2CW77
TrEMBL
UniProt Splice Variant
Entrez Gene 100144748
UniGene Hs.313888 Hs.559820
RefSeq NM_001126049
HUGO HGNC:37212
OMIM 612105
CCDS CCDS44454
HPRD
IMGT
EMBL AC063965 EU552092
GenPept ACB45456
RNA Seq Atlas 100144748