Homo sapiens Gene: KLLN

Summary
InnateDB Gene IDBG-306974.3
Last Modified 2012-02-14   [Report errors or provide feedback]
Gene Symbol KLLN
Gene Name killin, p53-regulated DNA replication inhibitor
Synonyms CWS4; KILLIN
Species Homo sapiens
Ensembl Gene ENSG00000227268
Encoded Proteins
IDBP-381908 killin, p53-regulated DNA replication inhibitor
Entrez Gene
Summary The protein encoded by this intronless gene is found in the nucleus, where it can inhibit DNA synthesis and promote S phase arrest coupled to apoptosis. The expression of this DNA binding protein is upregulated by transcription factor p53. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 10: 89618918-89623194
Strand Reverse strand
Band q23.31
Transcripts
ENST00000445946  ENSP00000392204
Interactions
Number of Interactions   This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
 
Gene Ontology
Accession GO Term
Molecular Function
GO:0003677 DNA binding
Biological Process
GO:0006915 apoptotic process
GO:0007049 cell cycle
Cellular Component
GO:0005634 nucleus
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt B2CW77 
TrEMBL
UniProt Splice Variant
Entrez Gene 100144748 
UniGene Hs.313888 Hs.559820
RefSeq NM_001126049 
HUGO 37212 
OMIM 612105
CCDS CCDS44454 
HPRD
IMGT
EMBL AC063965 EU552092
GenPept ACB45456 
ImmGen KLLN (murine) 
RNA Seq Atlas 100144748