Version 5.4
Homo sapiens Gene: RBL2
Summary
InnateDB Gene IDBG-30965.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RBL2
Gene Name retinoblastoma-like 2 (p130)
Synonyms P130; Rb2
Species Homo sapiens
Ensembl Gene ENSG00000103479
Encoded Proteins
IDBP-30967
retinoblastoma-like 2 (p130)
IDBP-603481
retinoblastoma-like 2 (p130)
IDBP-595952
retinoblastoma-like 2 (p130)
IDBP-752127
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 16:53433977-53491649
Strand Forward strand
Band q12.2
Transcripts
ENST00000262133 ENSP00000262133
ENST00000379935
ENST00000544405 ENSP00000443744
ENST00000544545 ENSP00000444685
ENST00000561512
ENST00000564605
ENST00000567964 ENSP00000462464
ENST00000562850
ENST00000562837
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 344 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 347 [view]
Protein-Protein 89 [view]
Protein-DNA 257 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0006351 transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0007049 cell cycle
GO:0016568 chromatin modification
GO:0043550 regulation of lipid kinase activity
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription factor complex
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031666
View Gene Order
ENSBTAG00000016243
Not yet available
Pathways
NETPATH
NetPath_5
ID pathway
NetPath_7
TGF_beta_Receptor pathway
REACTOME
REACT_111214
G0 and Early G1 pathway
REACT_821
Cyclin D associated events in G1 pathway
REACT_1590
G1 Phase pathway
REACT_21267
Mitotic G1-G1/S phases pathway
REACT_115566
Cell Cycle pathway
REACT_152
Cell Cycle, Mitotic pathway
KEGG
hsa04110
Cell cycle pathway
INOH
PID NCI
foxopathway
FoxO family signaling
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.513609 Hs.601070 Hs.611879
RefSeq NM_005611 XM_005256083
HUGO
OMIM
CCDS CCDS10748
HPRD 01576
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca