Version 5.4
| Homo sapiens Gene: ADH6 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-31160.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | ADH6 | ||||||||||||||||||
| Gene Name | alcohol dehydrogenase 6 (class V) | ||||||||||||||||||
| Synonyms | ADH-5 | ||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000172955 | ||||||||||||||||||
| Encoded Proteins |
alcohol dehydrogenase 6 (class V)
alcohol dehydrogenase 6 (class V)
alcohol dehydrogenase 6 (class V)
alcohol dehydrogenase 6 (class V)
alcohol dehydrogenase 6 (class V)
alcohol dehydrogenase 6 (class V)
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| Protein Structure | |||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
This gene encodes class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This gene is expressed in the stomach as well as in the liver, and it contains a glucocorticoid response element upstream of its 5' UTR, which is a steroid hormone receptor binding site. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] This gene encodes class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This gene is expressed in the stomach as well as in the liver, and it contains a glucocorticoid response element upstream of its 5\' UTR, which is a steroid hormone receptor binding site. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 4:99202638-99219537 | ||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||
| Band | q23 | ||||||||||||||||||
| Transcripts | |||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
| No orthologs found for this gene | |||||||||||||||||||
| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
Ethanol oxidation pathway
Metabolism pathway
Biological oxidations pathway
Phase 1 - Functionalization of compounds pathway
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| KEGG |
Glycolysis / Gluconeogenesis pathway
Retinol metabolism pathway
Fatty acid degradation pathway
Tyrosine metabolism pathway
Metabolism of xenobiotics by cytochrome P450 pathway
Drug metabolism pathway
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| INOH |
Tyrosine metabolism pathway
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| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | |||||||||||||||||||
| TrEMBL | |||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 130 | ||||||||||||||||||
| UniGene | Hs.586161 | ||||||||||||||||||
| RefSeq | NM_000672 NM_001102470 XM_005262731 | ||||||||||||||||||
| HUGO | HGNC:255 | ||||||||||||||||||
| OMIM | 103735 | ||||||||||||||||||
| CCDS | CCDS3647 CCDS43255 | ||||||||||||||||||
| HPRD | 00067 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | |||||||||||||||||||
| GenPept | |||||||||||||||||||
| RNA Seq Atlas | 130 | ||||||||||||||||||