Version 5.4
Homo sapiens Gene: SMC6
Summary
InnateDB Gene IDBG-31220.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SMC6
Gene Name structural maintenance of chromosomes 6
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000163029
Encoded Proteins
IDBP-31224
structural maintenance of chromosomes 6
IDBP-31226
structural maintenance of chromosomes 6
IDBP-295062
structural maintenance of chromosomes 6
IDBP-365015
structural maintenance of chromosomes 6
IDBP-365029
structural maintenance of chromosomes 6
IDBP-365032
structural maintenance of chromosomes 6
IDBP-365037
structural maintenance of chromosomes 6
IDBP-810967
structural maintenance of chromosomes 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:17663812-17800242
Strand Reverse strand
Band p24.2
Transcripts
ENST00000381272 ENSP00000370672
ENST00000351948 ENSP00000323439
ENST00000402989 ENSP00000384539
ENST00000448223 ENSP00000404092
ENST00000446852 ENSP00000408644
ENST00000430591 ENSP00000412246
ENST00000428868 ENSP00000415352
ENST00000481708
ENST00000489535
ENST00000621152 ENSP00000480257
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0000722 telomere maintenance via recombination
GO:0000724 double-strand break repair via homologous recombination
GO:0090398 cellular senescence
Cellular Component
GO:0000781 chromosome, telomeric region
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0016605 PML body
GO:0030915 Smc5-Smc6 complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020608
View Gene Order
ENSBTAG00000018256
Not yet available
Cross-References
SwissProt
TrEMBL C9JEF0 C9JMN1
UniProt Splice Variant
Entrez Gene 79677
UniGene Hs.526728 Hs.617590 Hs.733296
RefSeq NM_001142286 NM_024624 XM_005262628
HUGO HGNC:20466
OMIM 609387
CCDS CCDS1690
HPRD 10242
IMGT
EMBL AC093731 AC097377
GenPept
RNA Seq Atlas 79677

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca