Version 5.4
Homo sapiens Gene: TUBA1C
Summary
InnateDB Gene IDBG-31264.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TUBA1C
Gene Name tubulin, alpha 1c
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000167553
Encoded Proteins
IDBP-31268
tubulin, alpha 1c
IDBP-589482
tubulin, alpha 1c
IDBP-588076
tubulin, alpha 1c
IDBP-593008
tubulin, alpha 1c
IDBP-590954
tubulin, alpha 1c
IDBP-583866
tubulin, alpha 1c
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:49188736-49274603
Strand Forward strand
Band q13.12
Transcripts
ENST00000301072 ENSP00000301072
ENST00000549554
ENST00000550574
ENST00000541364 ENSP00000443475
ENST00000549818 ENSP00000447669
ENST00000552448 ENSP00000448646
ENST00000552125 ENSP00000447910
ENST00000549183 ENSP00000448211
ENST00000548470
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 91 experimentally validated interaction(s) in this database.
Experimentally validated
Total 91 [view]
Protein-Protein 91 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005198 structural molecule activity
GO:0005200 structural constituent of cytoskeleton
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0006457 protein folding
GO:0007017 microtubule-based process
GO:0030705 cytoskeleton-dependent intracellular transport
GO:0044267 cellular protein metabolic process
GO:0051084 'de novo' posttranslational protein folding
GO:0051258 protein polymerization
GO:0051301 cell division
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005874 microtubule
GO:0005881 cytoplasmic microtubule
GO:0043234 protein complex
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_150425
Resolution of Sister Chromatid Cohesion pathway
REACT_682
Mitotic Prometaphase pathway
REACT_150471
Separation of Sister Chromatids pathway
REACT_15510
Recruitment of NuMA to mitotic centrosomes pathway
REACT_15296
Recruitment of mitotic centrosome proteins and complexes pathway
REACT_121399
MHC class II antigen presentation pathway
REACT_25201
Kinesins pathway
REACT_24970
Factors involved in megakaryocyte development and platelet production pathway
REACT_16967
Post-chaperonin tubulin folding pathway pathway
REACT_16936
Prefoldin mediated transfer of substrate to CCT/TriC pathway
REACT_16956
Formation of tubulin folding intermediates by CCT/TriC pathway
REACT_11039
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane pathway
REACT_11050
Transport of connexons to the plasma membrane pathway
REACT_9509
Gap junction assembly pathway
REACT_147867
Translocation of GLUT4 to the plasma membrane pathway
REACT_22365
Recycling pathway of L1 pathway
REACT_22205
L1CAM interactions pathway
REACT_16952
Protein folding pathway
REACT_111045
Developmental Biology pathway
REACT_228134
Signaling by Hedgehog pathway
REACT_18266
Axon guidance pathway
REACT_111102
Signal Transduction pathway
REACT_267634
Hedgehog 'off' state pathway
REACT_9411
Gap junction trafficking pathway
REACT_17004
Chaperonin-mediated protein folding pathway
REACT_115566
Cell Cycle pathway
REACT_17015
Metabolism of proteins pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_17029
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding pathway
REACT_910
M Phase pathway
REACT_1275
Mitotic Anaphase pathway
REACT_15479
Centrosome maturation pathway
REACT_2203
G2/M Transition pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_21391
Mitotic G2-G2/M phases pathway
REACT_9480
Gap junction trafficking and regulation pathway
REACT_604
Hemostasis pathway
REACT_11123
Membrane Trafficking pathway
REACT_150314
Mitotic Metaphase and Anaphase pathway
KEGG
hsa05130
Pathogenic Escherichia coli infection pathway
hsa04540
Gap junction pathway
hsa04145
Phagosome pathway
INOH
PID NCI
Cross-References
SwissProt Q9BQE3
TrEMBL F5H5D3 F8VRK0 F8VRK1 F8VRZ4 F8VS66 F8VWV9 F8VX09 F8VXZ7
UniProt Splice Variant
Entrez Gene 84790
UniGene Hs.652390 Hs.739076
RefSeq NM_032704
HUGO HGNC:20768
OMIM
CCDS CCDS8782
HPRD
IMGT
EMBL AC010173 AC011603 AC125611 BC004949 BC005946 BC011790 BC019298 BC021088 BC051297 BC063036
GenPept AAH04949 AAH05946 AAH11790 AAH19298 AAH21088 AAH51297 AAH63036
RNA Seq Atlas 84790

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca