Homo sapiens Gene: PTPN23
Summary
InnateDB Gene IDBG-31480.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PTPN23
Gene Name protein tyrosine phosphatase, non-receptor type 23
Synonyms HD-PTP; HDPTP; PTP-TD14;
Species Homo sapiens
Ensembl Gene ENSG00000076201
Encoded Proteins
protein tyrosine phosphatase, non-receptor type 23
protein tyrosine phosphatase, non-receptor type 23
protein tyrosine phosphatase, non-receptor type 23
Protein Structure
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:47381011-47413441
Strand Forward strand
Band p21.31
Transcripts
ENST00000265562 ENSP00000265562
ENST00000456221 ENSP00000396328
ENST00000462998
ENST00000477276
ENST00000495653
ENST00000602307 ENSP00000473266
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 41 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 41 [view]
Protein-Protein 41 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004725 protein tyrosine phosphatase activity
GO:0005515 protein binding
GO:0016791 phosphatase activity
Biological Process
GO:0006470 protein dephosphorylation
GO:0015031 protein transport
GO:0016311 dephosphorylation
GO:0030334 regulation of cell migration
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0060271 cilium morphogenesis
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005769 early endosome
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0036064 ciliary basal body
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
EGFR1 pathway
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q9H3S7
TrEMBL B4DST5 C9JD91 R4GMM7
UniProt Splice Variant
Entrez Gene 25930
UniGene Hs.25524
RefSeq NM_015466 XM_005265031 XM_005265033
HUGO HGNC:14406
OMIM 606584
CCDS CCDS2754
HPRD 05959
IMGT
EMBL AB025194 AB040904 AC099778 AF169350 AF290614 AK289502 AK299906 AL110210 BC004881 BC027711 BC089042 BT009758 CH471055
GenPept AAD50276 AAH04881 AAH27711 AAH89042 AAK28025 AAP88760 BAA95995 BAB19280 BAF82191 BAG61747 CAB53676 EAW64823
ImmGen PTPN23 (murine)
RNA Seq Atlas 25930