Version 5.4
Homo sapiens Gene: MCRS1
Summary
InnateDB Gene IDBG-31596.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MCRS1
Gene Name microspherule protein 1
Synonyms ICP22BP; INO80Q; MCRS2; MSP58; P78
Species Homo sapiens
Ensembl Gene ENSG00000187778
Encoded Proteins
IDBP-31598
microspherule protein 1
IDBP-31600
microspherule protein 1
IDBP-604239
microspherule protein 1
IDBP-604240
microspherule protein 1
IDBP-604244
microspherule protein 1
IDBP-604245
microspherule protein 1
IDBP-604248
microspherule protein 1
IDBP-604249
microspherule protein 1
IDBP-604250
microspherule protein 1
IDBP-604251
microspherule protein 1
IDBP-604252
microspherule protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:49556544-49568153
Strand Reverse strand
Band q13.12
Transcripts
ENST00000343810 ENSP00000345358
ENST00000357123 ENSP00000349640
ENST00000551598 ENSP00000448947
ENST00000548602 ENSP00000447739
ENST00000551625
ENST00000550165 ENSP00000448056
ENST00000552596
ENST00000548646 ENSP00000448700
ENST00000547182
ENST00000549000
ENST00000553173 ENSP00000447514
ENST00000548334 ENSP00000450352
ENST00000548596 ENSP00000449343
ENST00000549528 ENSP00000447592
ENST00000552206
ENST00000546244 ENSP00000444982
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 64 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 64 [view]
Protein-Protein 64 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0043995 histone acetyltransferase activity (H4-K5 specific)
GO:0043996 histone acetyltransferase activity (H4-K8 specific)
GO:0046972 histone acetyltransferase activity (H4-K16 specific)
Biological Process
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0006325 chromatin organization
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006464 cellular protein modification process
GO:0043981 histone H4-K5 acetylation
GO:0043982 histone H4-K8 acetylation
GO:0043984 histone H4-K16 acetylation
Cellular Component
GO:0000123 histone acetyltransferase complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0031011 Ino80 complex
GO:0071339 MLL1 complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037570
View Gene Order
ENSBTAG00000019281
Not yet available
Pathways
NETPATH
REACTOME
REACT_172610
HATs acetylate histones pathway
REACT_172623
Chromatin organization pathway
REACT_172633
Chromatin modifying enzymes pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.25313
RefSeq NM_001012300 NM_001278341 NM_006337 XM_005268572
HUGO
OMIM
CCDS CCDS31795 CCDS61118 CCDS8787
HPRD 11298
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca