Version 5.4
Homo sapiens Gene: MUC17
Summary
InnateDB Gene IDBG-32878.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MUC17
Gene Name mucin 17, cell surface associated
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000169876
Encoded Proteins
IDBP-32880
mucin 17, cell surface associated
IDBP-32882
mucin 17, cell surface associated
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Membrane mucins, such as MUC17, function in epithelial cells to provide cytoprotection, maintain luminal structure, provide signal transduction, and confer antiadhesive properties upon cancer cells that lose their apical/basal polarization.[supplied by OMIM, Apr 2004]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:101020072-101058745
Strand Forward strand
Band q22.1
Transcripts
ENST00000306151 ENSP00000302716
ENST00000379439 ENSP00000368751
ENST00000470303
ENST00000497859
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030165 PDZ domain binding
GO:0030197 extracellular matrix constituent, lubricant activity
Biological Process
GO:0016266 O-glycan processing
GO:0019725 cellular homeostasis
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005576 extracellular region
GO:0005796 Golgi lumen
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000037390
View Gene Order
Pathways
NETPATH
REACTOME
REACT_115835
Termination of O-glycan biosynthesis pathway
REACT_115606
O-linked glycosylation of mucins pathway
REACT_22161
Post-translational protein modification pathway
REACT_200727
O-linked glycosylation pathway
REACT_17015
Metabolism of proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q685J3
TrEMBL A1A4F7
UniProt Splice Variant
Entrez Gene 140453
UniGene Hs.271819
RefSeq NM_001040105
HUGO HGNC:16800
OMIM 608424
CCDS CCDS34711
HPRD 16335
IMGT
EMBL AC105446 AF016693 AF430017 AJ606307 AJ606308 BC126315
GenPept AAB71686 AAI26316 AAL89737 CAE54435 CAE54436
RNA Seq Atlas 140453

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca