Version 5.4
Homo sapiens Gene: MYO5B
Summary
InnateDB Gene IDBG-3288.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MYO5B
Gene Name myosin VB
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000167306
Encoded Proteins
IDBP-3290
myosin VB
IDBP-3292
myosin VB
IDBP-725687
IDBP-806840
myosin VB
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene, together with other proteins, may be involved in plasma membrane recycling. Mutations in this gene are associated with microvillous inclusion disease. [provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:49822813-50195093
Strand Reverse strand
Band q21.1
Transcripts
ENST00000285039 ENSP00000285039
ENST00000324581 ENSP00000315531
ENST00000587895
ENST00000586036
ENST00000585859
ENST00000592688 ENSP00000466368
ENST00000589568
ENST00000616031 ENSP00000479038
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000146 microfilament motor activity
GO:0003774 motor activity
GO:0003779 actin binding
GO:0005515 protein binding
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0017137 Rab GTPase binding
Biological Process
GO:0006833 water transport
GO:0008152 metabolic process
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016459 myosin complex
GO:0030659 cytoplasmic vesicle membrane
GO:0043234 protein complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000025885
View Gene Order
ENSBTAG00000019455
Not yet available
Pathways
NETPATH
REACTOME
REACT_24023
Vasopressin regulates renal water homeostasis via Aquaporins pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_23887
Aquaporin-mediated transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.535208 Hs.599817 Hs.605396 Hs.648987 Hs.700876 Hs.720076
RefSeq NM_001080467
HUGO
OMIM
CCDS CCDS42436
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca