Version 5.4
Homo sapiens Gene: VGF
Summary
InnateDB Gene IDBG-33066.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VGF
Gene Name VGF nerve growth factor inducible
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000128564
Encoded Proteins
IDBP-33068
VGF nerve growth factor inducible
IDBP-384131
VGF nerve growth factor inducible
IDBP-810811
VGF nerve growth factor inducible
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:101162509-101165593
Strand Reverse strand
Band q22.1
Transcripts
ENST00000249330 ENSP00000249330
ENST00000445482 ENSP00000400884
ENST00000611537 ENSP00000480817
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 5 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005184 neuropeptide hormone activity
GO:0008083 growth factor activity
Biological Process
GO:0001541 ovarian follicle development
GO:0002021 response to dietary excess
GO:0006091 generation of precursor metabolites and energy
GO:0009409 response to cold
GO:0019953 sexual reproduction
GO:0030073 insulin secretion
GO:0032868 response to insulin
GO:0042593 glucose homeostasis
GO:0042742 defense response to bacterium
GO:0051591 response to cAMP
Cellular Component
GO:0005615 extracellular space
GO:0030133 transport vesicle
GO:0031410 cytoplasmic vesicle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037428
View Gene Order
ENSBTAG00000009868
Not yet available
Cross-References
SwissProt O15240
TrEMBL
UniProt Splice Variant
Entrez Gene 7425
UniGene Hs.587325
RefSeq XM_005250561 NM_003378 XM_005250560
HUGO HGNC:12684
OMIM 602186
CCDS CCDS5712
HPRD 03717
IMGT
EMBL AC004876 BC063835 CH471197 Y12661
GenPept AAD45830 AAH63835 CAA73210 EAW50201
RNA Seq Atlas 7425

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca