Version 5.4
Homo sapiens Gene: ENOSF1
Summary
InnateDB Gene IDBG-331.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ENOSF1
Gene Name enolase superfamily member 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000132199
Encoded Proteins
IDBP-335
enolase superfamily member 1
IDBP-337
enolase superfamily member 1
IDBP-339
enolase superfamily member 1
IDBP-726871
IDBP-807471
enolase superfamily member 1
IDBP-727292
IDBP-727325
IDBP-725654
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene was originally identified as a naturally occurring antisense transcript to the human thymidylate synthase gene. Alternate splice variants have been described, one of which (named rTSalpha) represents an alternate 3'UTR that is complementary to the 3'UTR and terminal intron of the thymidylate synthase (TS) RNA and down-regulates TS expression. Other transcript variants (rTSbeta and rTSgamma) do not overlap the TS locus. The function of this gene appears to be primarily to regulate expression of the TS locus both via the antisense transcript as well as through the encoded proteins. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:670324-712676
Strand Reverse strand
Band p11.32
Transcripts
ENST00000340116 ENSP00000345974
ENST00000251101 ENSP00000251101
ENST00000383578 ENSP00000373072
ENST00000584453 ENSP00000463448
ENST00000581906
ENST00000582745
ENST00000583771 ENSP00000473632
ENST00000580605
ENST00000583973
ENST00000584259
ENST00000581475 ENSP00000464614
ENST00000577334
ENST00000585128 ENSP00000462925
ENST00000578651
ENST00000580982 ENSP00000463425
ENST00000581332
ENST00000579053
ENST00000584706
ENST00000585004
ENST00000584646
ENST00000581928
ENST00000578647
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0003824 catalytic activity
GO:0016853 isomerase activity
GO:0050023 L-fuconate dehydratase activity
Biological Process
GO:0008152 metabolic process
GO:0009063 cellular amino acid catabolic process
GO:0044275 cellular carbohydrate catabolic process
Cellular Component
GO:0005575 cellular_component
GO:0005739 mitochondrion
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.731510
RefSeq NM_001126123 NM_017512 NM_202758 XM_005258118
HUGO
OMIM
CCDS CCDS11822 CCDS11823 CCDS45821
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca