Version 5.4
Homo sapiens Gene: POLR3G
Summary
InnateDB Gene IDBG-33164.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POLR3G
Gene Name polymerase (RNA) III (DNA directed) polypeptide G (32kD)
Synonyms RPC32; RPC7
Species Homo sapiens
Ensembl Gene ENSG00000113356
Encoded Proteins
IDBP-231481
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
IDBP-479284
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
IDBP-477520
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
IDBP-481332
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
IDBP-479512
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
IDBP-478563
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
IDBP-478837
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
IDBP-809359
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 5:90471748-90514553
Strand Forward strand
Band q14.3
Transcripts
ENST00000399107 ENSP00000382058
ENST00000512239 ENSP00000424970
ENST00000505345 ENSP00000427412
ENST00000503373 ENSP00000422892
ENST00000503973 ENSP00000422164
ENST00000504930 ENSP00000421637
ENST00000514483 ENSP00000425617
ENST00000622335 ENSP00000478166
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
Experimentally validated
Total 14 [view]
Protein-Protein 12 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001056 RNA polymerase III activity
GO:0003899 DNA-directed RNA polymerase activity
Biological Process
GO:0006359 regulation of transcription from RNA polymerase III promoter
GO:0006383 transcription from RNA polymerase III promoter
GO:0006384 transcription initiation from RNA polymerase III promoter
GO:0006385 transcription elongation from RNA polymerase III promoter
GO:0006386 termination of RNA polymerase III transcription
GO:0008283 cell proliferation
GO:0010467 gene expression
GO:0032481 positive regulation of type I interferon production
GO:0032728 positive regulation of interferon-beta production
GO:0045087 innate immune response
GO:0045089 positive regulation of innate immune response
GO:0051607 defense response to virus
Cellular Component
GO:0000790 nuclear chromatin
GO:0005654 nucleoplasm
GO:0005666 DNA-directed RNA polymerase III complex
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000035834
View Gene Order
ENSBTAG00000044077
Not yet available
Pathways
NETPATH
REACTOME
REACT_22339
RNA Polymerase III Abortive And Retractive Initiation pathway
REACT_63
RNA Polymerase III Transcription Termination pathway
REACT_756
RNA Polymerase III Chain Elongation pathway
REACT_571
RNA Polymerase III Transcription Initiation From Type 3 Promoter pathway
REACT_1036
RNA Polymerase III Transcription Initiation From Type 2 Promoter pathway
REACT_347
RNA Polymerase III Transcription Initiation From Type 1 Promoter pathway
REACT_281
RNA Polymerase III Transcription Initiation pathway
REACT_6802
Innate Immune System pathway
REACT_6900
Immune System pathway
REACT_1371
RNA Polymerase III Transcription pathway
REACT_21352
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_118823
Cytosolic sensors of pathogen-associated DNA pathway
REACT_71
Gene Expression pathway
KEGG
hsa00240
Pyrimidine metabolism pathway
hsa00230
Purine metabolism pathway
hsa03020
RNA polymerase pathway
hsa04623
Cytosolic DNA-sensing pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.282387 Hs.629725
RefSeq NM_006467 XM_005248404 XM_006714519 XM_006714520
HUGO
OMIM
CCDS CCDS43337
HPRD 17881
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca