Version 5.4
Homo sapiens Gene: PFN4
Summary
InnateDB Gene IDBG-33553.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PFN4
Gene Name profilin family, member 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000176732
Encoded Proteins
IDBP-33557
profilin family, member 4
IDBP-365981
profilin family, member 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:24115371-24123477
Strand Reverse strand
Band p23.3
Transcripts
ENST00000313213 ENSP00000322170
ENST00000436622 ENSP00000393504
ENST00000465360
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0008289 lipid binding
Biological Process
GO:0030036 actin cytoskeleton organization
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020639
View Gene Order
ENSBTAG00000003404
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04810
Regulation of actin cytoskeleton pathway
hsa05131
Shigellosis pathway
INOH
PID NCI
Cross-References
SwissProt Q8NHR9
TrEMBL
UniProt Splice Variant
Entrez Gene 375189
UniGene
RefSeq NM_199346 XM_005264292 XM_006712007
HUGO HGNC:31103
OMIM
CCDS CCDS1709
HPRD
IMGT
EMBL AC008073 AK292601 BC029523 CH471053
GenPept AAH29523 AAY14666 BAF85290 EAX00760 EAX00761
RNA Seq Atlas 375189

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca