Version 5.4
Homo sapiens Gene: SLC1A6
Summary
InnateDB Gene IDBG-34070.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC1A6
Gene Name solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
Synonyms EAAT4
Species Homo sapiens
Ensembl Gene ENSG00000105143
Encoded Proteins
IDBP-34072
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
IDBP-374452
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
IDBP-594197
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
IDBP-761597
IDBP-761047
IDBP-760576
IDBP-765570
IDBP-765941
IDBP-764786
IDBP-759981
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:14950034-15022990
Strand Reverse strand
Band p13.12
Transcripts
ENST00000221742 ENSP00000221742
ENST00000430939 ENSP00000409386
ENST00000544886 ENSP00000446175
ENST00000599636 ENSP00000472837
ENST00000601761 ENSP00000471129
ENST00000595863 ENSP00000469551
ENST00000598504 ENSP00000471781
ENST00000594383 ENSP00000472133
ENST00000596697
ENST00000600144 ENSP00000471038
ENST00000597262 ENSP00000471562
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005313 L-glutamate transmembrane transporter activity
GO:0015183 L-aspartate transmembrane transporter activity
GO:0017153 sodium:dicarboxylate symporter activity
Biological Process
GO:0006811 ion transport
GO:0006835 dicarboxylic acid transport
GO:0007268 synaptic transmission
GO:0015810 aspartate transport
GO:0015813 L-glutamate transport
GO:0042391 regulation of membrane potential
GO:0055085 transmembrane transport
Cellular Component
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000005357
View Gene Order
ENSBTAG00000013502
Not yet available
Pathways
NETPATH
REACTOME
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_12591
Glutamate Neurotransmitter Release Cycle pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_13685
Neuronal System pathway
REACT_13477
Transmission across Chemical Synapses pathway
REACT_13723
Neurotransmitter Release Cycle pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.515217
RefSeq NM_001272087 NM_001272088 NM_005071 XM_006722842 XM_006722843 XM_006722844
HUGO
OMIM
CCDS CCDS12321 CCDS62578
HPRD 09005
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca