Version 5.4
Homo sapiens Gene: SKA1
Summary
InnateDB Gene IDBG-3435.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SKA1
Gene Name spindle and kinetochore associated complex subunit 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000154839
Encoded Proteins
IDBP-3437
spindle and kinetochore associated complex subunit 1
IDBP-233043
spindle and kinetochore associated complex subunit 1
IDBP-369770
spindle and kinetochore associated complex subunit 1
IDBP-726605
IDBP-728085
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 18:50374995-50394173
Strand Forward strand
Band q21.1
Transcripts
ENST00000285116 ENSP00000285116
ENST00000398452 ENSP00000381470
ENST00000417656 ENSP00000397222
ENST00000488454 ENSP00000467242
ENST00000494518 ENSP00000467559
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008017 microtubule binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0007059 chromosome segregation
GO:0007067 mitotic nuclear division
GO:0031110 regulation of microtubule polymerization or depolymerization
GO:0051301 cell division
Cellular Component
GO:0000940 condensed chromosome outer kinetochore
GO:0005829 cytosol
GO:0005876 spindle microtubule
GO:0015630 microtubule cytoskeleton
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036223
View Gene Order
ENSBTAG00000018216
Not yet available
Pathways
NETPATH
REACTOME
REACT_150425
Resolution of Sister Chromatid Cohesion pathway
REACT_682
Mitotic Prometaphase pathway
REACT_150471
Separation of Sister Chromatids pathway
REACT_115566
Cell Cycle pathway
REACT_910
M Phase pathway
REACT_1275
Mitotic Anaphase pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_150314
Mitotic Metaphase and Anaphase pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q96BD8
TrEMBL A0A024R294 K7EP61 K7EPW0
UniProt Splice Variant
Entrez Gene 220134
UniGene Hs.134726
RefSeq NM_001039535 NM_145060
HUGO HGNC:28109
OMIM
CCDS CCDS11946
HPRD 12689
IMGT
EMBL AC105227 AK303464 AK313968 BC015706 CH471096
GenPept AAH15706 BAG36683 BAG64506 EAW62971 EAW62972 EAW62973
RNA Seq Atlas 220134

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca